Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1197428 | 0.84 | CALCRL (0.47) | — | |
| SCHEMBL1198387 | 0.78 | LMNA (0.41) | LMNASMN1; SMN2SLC18A3KMT2ASRD5A1 | |
| SCHEMBL1198385 | 0.78 | LMNA (0.41) | LMNASMN1; SMN2SLC18A3KMT2ASRD5A1 | |
| SCHEMBL1198383 | 0.78 | LMNA (0.41) | LMNASMN1; SMN2SLC18A3KMT2ASRD5A1 | |
| SCHEMBL1197441 | 0.77 | SLC18A3 (0.41) | LMNASMN1; SMN2SLC18A3KMT2ASRD5A1 | |
| SCHEMBL1198584 | 0.77 | SLC18A3 (0.41) | LMNASMN1; SMN2SLC18A3KMT2ASRD5A1 | |
| SCHEMBL1197439 | 0.77 | SLC18A3 (0.41) | LMNASMN1; SMN2SLC18A3KMT2ASRD5A1 | |
| SCHEMBL12811890 | 0.77 | LMNA (0.38) | LMNASMN1; SMN2SLC18A3KMT2ASRD5A1 | |
| SCHEMBL1198583 | 0.77 | SLC18A3 (0.41) | LMNASMN1; SMN2SLC18A3KMT2ASRD5A1 | |
| SCHEMBL1197443 | 0.77 | SLC18A3 (0.41) | LMNASMN1; SMN2SLC18A3KMT2ASRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893052-B2 | CGRP receptor antagonists | MERCK SHARP & DOHME LLC | 2011-02-22 | — | — | US | disclosed |