SCHEMBL11983050

SCHEMBL11983050

CN1C(=S)N(C2(N)CCOCC2)CC1c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 7/20 0.34
MAOA P21397 7/20 0.34
MAOB P27338 7/20 0.34
GAA P10253 1/20 0.33
ATM Q13315 2/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
PIK3C3 Q8NEB9 1/20 0.32
TSHR P16473 1/20 0.31
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11973066 0.71 ATM (0.44) GAAATMTSHR
SCHEMBL6439879 0.70 GAA (0.44) MAOAMAOBGAAATMCHRNB2
SCHEMBL11983128 0.68
SCHEMBL11983242 0.65
SCHEMBL1070651 0.59 CHRNB2 (0.59) MAOAMAOBATMCHRNB2CHRNB4
SCHEMBL14870536 0.59 CHRNB2 (0.59) MAOAMAOBATMCHRNB2CHRNB4
SCHEMBL11775882 0.59 KMT2A (0.45) KDM1AMAOAMAOBCHRNB2CHRNB4
SCHEMBL16130557 0.59 CHRNB2 (0.55) ATMCHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL16130585 0.59 CHRNB2 (0.55) ATMCHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL16596749 0.59 GAA (0.42) MAOAMAOBGAAATMCHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8241740-B2 Layer laminated to support; ionization radiation; curing using free radical catalyst; image display and polarization plates FUJIFILM CORPORATION (JP) 2012-08-14 US disclosed
US-20080234461-A1 Antireflective Film, Method of Manufacturing Antireflective Film, Polarizing Plate and Image Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed