Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.58 |
| ▸ | CALML3 | P27482 | 6/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SDHA | P31040 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10266890 | 0.90 | MAOA (0.60) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3182633 | 0.89 | MAOA (0.61) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1394333 | 0.89 | MAOA (0.61) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393378 | 0.89 | MAOA (0.61) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393554 | 0.89 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3095610 | 0.88 | MAOA (0.58) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393940 | 0.88 | MAOA (0.60) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3181230 | 0.88 | MAOA (0.60) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL10196230 | 0.88 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1394891 | 0.88 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656370-B1 | BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB X PHARMACEUTICALS INC (US) | 2012-08-15 | — | — | EP | disclosed |