Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10091441 | 0.88 | PTGES (0.42) | PTGESCNR2CNR1ABHD12DRD2 | |
| SCHEMBL672445 | 0.88 | PTGES (0.42) | PTGESCNR2CNR1ABHD12DRD2 | |
| SCHEMBL672444 | 0.88 | PTGES (0.42) | PTGESCNR2CNR1ABHD12DRD2 | |
| SCHEMBL671327 | 0.76 | PTGES (0.44) | PTGESCNR2CNR1 | |
| SCHEMBL11985261 | 0.76 | PTGES (0.40) | PTGESCNR2CNR1ABHD12DRD2 | |
| SCHEMBL672703 | 0.76 | PTGES (0.44) | PTGESCNR2CNR1 | |
| SCHEMBL11907883 | 0.75 | CNR2 (0.37) | PTGESCNR2CNR1ABHD12ALDH1A1 | |
| SCHEMBL11907880 | 0.75 | CNR2 (0.37) | PTGESCNR2CNR1ABHD12ALDH1A1 | |
| SCHEMBL11908364 | 0.75 | PTGES (0.41) | PTGESCNR2CNR1DRD2DRD3 | |
| SCHEMBL11908368 | 0.75 | PTGES (0.41) | PTGESCNR2CNR1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208839-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208839-A1 | NEW COMPOUNDS | PTGER1, PTGS1, PTGES | PTGES 3/4885CNR2 85/4885CNR1 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.