SCHEMBL11986129

SCHEMBL11986129

C=C(C)C(=O)OCOc1ccc(C(=O)Oc2ccc(C(c3ccc(OC(=O)c4ccc(OCOC(=O)C(=C)C)cc4F)cc3)(C(F)(F)F)C(F)(F)F)cc2)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.37
MAOA P21397 1/20 0.35
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
GSTP1 P09211 3/20 0.33
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17720308 0.93 POLB (0.43) MAOBKMT2APOLBAPEX1HTT
SCHEMBL13829007 0.90 MAOB (0.43) MAOBMAOAALDH1A1KMT2APOLB
SCHEMBL13932727 0.90 POLB (0.45) MAOBMAOAKMT2APOLBAPEX1
SCHEMBL11986087 0.90 GSTP1 (0.40) ALDH1A1KMT2APOLBGAAGSTP1
SCHEMBL13932734 0.89 POLB (0.47) MAOBMAOAKMT2APOLBAPEX1
SCHEMBL16746160 0.87 MAOB (0.38) MAOBMAOAALDH1A1KMT2APOLB
SCHEMBL11986132 0.84 CYP11B1 (0.34) MAOBMAOACYP11B1CYP11B2ALDH1A1
SCHEMBL11986133 0.84 TDP1 (0.43) MAOBKMT2APOLBMAPTAPEX1
SCHEMBL11986151 0.83 MAPT (0.41) MAOBMAOAALDH1A1KMT2APOLB
SCHEMBL11986143 0.83 FFAR1 (0.35) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315728-B2 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film JNC CORPORATION (JP) 2016-04-19 US disclosed
US-20150361345-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-12-17 US disclosed
US-20150177567-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THEREOF CHI MEI CORPORATION (TW) 2015-06-25 US disclosed
US-8419973-B2 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8246855-B2 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC CORPORATION (JP) 2012-08-21 US disclosed
US-20100151154-A1 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film CHISSO CORPORATION 2010-06-17 US disclosed
US-20100143612-A1 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film CHISSO CORPORATION 2010-06-10 US disclosed
US-20100051866-A1 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC PETROCHEMICAL CORPORATION (JP) 2010-03-04 US disclosed