SCHEMBL11986151

SCHEMBL11986151

C=C(C)C(=O)OCOc1ccc(C(=O)Oc2ccc(S(=O)(=O)c3ccc(OC(=O)c4ccc(OCOC(=O)C(=C)C)cc4F)cc3)cc2)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
POLB P06746 1/20 0.41
PKM P14618 1/20 0.41
MAOB P27338 4/20 0.38
MAOA P21397 1/20 0.37
ELANE P08246 2/20 0.36
GAA P10253 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 2/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13829007 0.92 MAOB (0.43) POLBMAOBMAOAELANEALDH1A1
SCHEMBL13962710 0.89 POLB (0.48) MAPTPOLBPKMMAOBKMT2A
SCHEMBL11986105 0.88 POLB (0.42) MAPTPOLBPKMELANEGAA
SCHEMBL14026829 0.85 POLB (0.45) MAPTPOLBPKMGAANPSR1
SCHEMBL16746160 0.85 MAOB (0.38) MAPTPOLBMAOBMAOAGAA
SCHEMBL13932744 0.84 POLB (0.44) MAPTPOLBPKMMAOBKMT2A
SCHEMBL11986152 0.83 POLB (0.36) MAPTPOLBPKMMAOBMAOA
SCHEMBL12242783 0.83 HTT (0.43) POLBMAOBMAOAELANEALDH1A1
SCHEMBL11986129 0.83 MAOB (0.37) MAPTPOLBMAOBMAOAGAA
SCHEMBL11986154 0.82 PKM (0.41) MAPTPOLBPKMELANEGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315728-B2 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film JNC CORPORATION (JP) 2016-04-19 US disclosed
US-8419973-B2 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8246855-B2 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC CORPORATION (JP) 2012-08-21 US disclosed
US-20100151154-A1 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film CHISSO CORPORATION 2010-06-17 US disclosed
US-20100143612-A1 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film CHISSO CORPORATION 2010-06-10 US disclosed
US-20100051866-A1 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC PETROCHEMICAL CORPORATION (JP) 2010-03-04 US disclosed