SCHEMBL11986239

SCHEMBL11986239

CC(COC(=O)OC(C)(C)C)OC(=O)OC(C)COC(=O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
HDAC6 Q9UBN7 2/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
PRKCA P17252 1/20 0.32
TSHR P16473 2/20 0.31
MAPK1 P28482 1/20 0.31
CA12 O43570 1/20 0.31
CA14 Q9ULX7 1/20 0.31
ELANE P08246 1/20 0.31
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11986238 0.94 CA1 (0.33) CA1CA2CA7HDAC6HDAC1
SCHEMBL19106181 0.93 HDAC6 (0.30) CA1CA2CA7HDAC6
SCHEMBL11986237 0.92 CA1 (0.33) CA1CA2CA7HDAC6HDAC1
SCHEMBL17194006 0.88
SCHEMBL6366841 0.85 TSHR (0.43) CA1CA2CA7HDAC6HDAC1
SCHEMBL17194007 0.85
SCHEMBL17194010 0.81
SCHEMBL4167268 0.81 TSHR (0.33) TSHR
SCHEMBL21757564 0.80 MAPK1 (0.45) CA1CA2CA7HDAC6HDAC1
SCHEMBL12604848 0.79 MAPK1 (0.48) CA1CA2CA7HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011758-B2 Aliphatic polycarbonate-based surface active agents SASOL CHEMICALS (USA) LLC (US) 2018-07-03 US disclosed
US-9994760-B2 Polycarbonate block copolymers SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2018-06-12 US disclosed
US-9884937-B2 Polymer compositions and methods SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2018-02-06 US disclosed
US-9834710-B2 Adhesive compositions and methods SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-12-05 US disclosed
US-9738784-B2 Polymer blends NOVOMER, INC. (US) 2017-08-22 US disclosed
US-9738760-B2 Aliphatic polycarbonate compositions and methods NOVOMER, INC. (US) 2017-08-22 US disclosed
US-20170145147-A1 HIGH STRENGTH POLYURETHANE FOAM COMPOSITIONS AND METHODS NOVOMER, INC. 2017-05-25 US disclosed
US-20170051106-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-02-23 US disclosed
US-20170022319-A1 ALIPHATIC POLYCARBONATE POLYOL COMPOSITIONS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-01-26 US disclosed
US-20160319064-A1 POLYMER COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2016-11-03 US disclosed
US-20130274401-A1 ADHESIVE COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-10-17 US disclosed
US-20130244864-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-09-19 US disclosed
US-20130209775-A1 POLYMER BLENDS NOVOMER, INC. (US) 2013-08-15 US disclosed
US-20130172482-A1 POLYMER COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-07-04 US disclosed
US-8470956-B2 Polycarbonate polyol compositions and methods NOVOMER, INC. (US) 2013-06-25 US disclosed
US-20130066044-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-03-14 US disclosed
US-8247520-B2 Polycarbonate polyol compositions and methods NOVOMER, INC. (US) 2012-08-21 US disclosed
US-20110257296-A1 TUNABLE POLYMER COMPOSITIONS NOVOMER, INC. (US) 2011-10-20 US disclosed
US-20110230580-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS Novomer, Inc (US) 2011-09-22 US disclosed
US-20110218127-A1 POLYCARBONATE BLOCK COPOLYMERS NOVOMER, INC. (US) 2011-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230580-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS PARG, PUF60, PICALM CA1 40/4885CA2 54/4885CA7 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.