Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 4/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18406976 | 0.95 | MAPT (0.47) | MAPTADRA2AADRA1ALMNAALDH1A1 | |
| SCHEMBL11986257 | 0.93 | MAPT (0.62) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL18406974 | 0.92 | MAPT (0.45) | MAPTADRA2AADRA1ALMNAALDH1A1 | |
| SCHEMBL15180215 | 0.89 | MAPT (0.43) | MAPTTSHRPRKCA | |
| SCHEMBL9964654 | 0.88 | MAPT (0.40) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL18406978 | 0.86 | MAPT (0.46) | MAPTADRA2AADRA1ALMNAALDH1A1 | |
| SCHEMBL15780104 | 0.86 | MAPT (0.41) | MAPTTSHRTDP1 | |
| SCHEMBL15383093 | 0.85 | MAPT (0.38) | MAPTTSHRTDP1 | |
| SCHEMBL822396 | 0.84 | MAPT (0.67) | MAPTADRA2AADRA1ALMNAALDH1A1 | |
| SCHEMBL9964659 | 0.83 | MAPT (0.39) | MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264728-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2016-09-15 | — | — | US | disclosed |
| US-9376531-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2016-06-28 | — | — | US | disclosed |
| US-20150299386-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2015-10-22 | — | — | US | disclosed |
| US-8921508-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20140046008-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2014-02-13 | — | — | US | disclosed |
| US-20130244864-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-09-19 | — | — | US | disclosed |
| US-8470956-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20130066044-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-03-14 | — | — | US | disclosed |
| US-8247520-B2 | Polycarbonate polyol compositions and methods | NOVOMER, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20110230580-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | Novomer, Inc (US) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230580-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | PARG, PUF60, PICALM | MAPT 3045/4885ADRA2A 4879/4885ADRA1A 4882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.