SCHEMBL11987166

SCHEMBL11987166

C=CC(=O)Oc1c(C(C)c2cc(C(C)(C)CC)cc(C(C)(C)C=C)c2O)cc(C(C)(C)CC)cc1C(C)(C)CC

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RXRA P19793 5/20 0.35
PPARG P37231 5/20 0.35
RARG P13631 4/20 0.35
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11987169 0.95 CYP1A2 (0.34) RXRAPPARGRARG
SCHEMBL11987168 0.94 RARG (0.31) RXRAPPARGRARG
SCHEMBL29353638 0.94 RXRA (0.37) RXRAPPARGRARGRARARARB
SCHEMBL29464292 0.94 RXRA (0.37) RXRAPPARGRARGRARARARB
SCHEMBL237192 0.94 RXRA (0.37) RXRAPPARGRARGRARARARB
SCHEMBL13356407 0.92 RXRA (0.36) RXRAPPARGRARGRARARARB
SCHEMBL11987170 0.92 CNR2 (0.34) RXRAPPARGRARG
SCHEMBL11987165 0.90
SCHEMBL4411077 0.90 CYP1A2 (0.39) RXRAPPARGRARGRARARARB
SCHEMBL16280978 0.90 RXRA (0.34) RXRAPPARGRARGRARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8246737-B2 Cellulose ester optical film, polarizing plate and liquid crystal display using the same, method of manufacturing cellulose ester optical film, and copolymer KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
US-20100104775-A1 ULTRAVIOLET ABSORBING POLYMER, CELLULOSE ESTER OPTICAL FILM, METHOD OF PRODUCING CELLULOSE ESTER OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 US disclosed
US-20100069535-A1 Cellulose Ester Optical Film, Polarizing Plate and Liquid Crystal Display Using the Same, Method of Manufacturing Cellulose Ester Optical Film, and Copolymer. KONICA MINOLTA OPTO, INC. (JP) 2010-03-18 US disclosed
US-20090155495-A1 PROCESS FOR PRODUCING CELLULOSE ACYLATE FILM, CELLULOSE ACYLATE FILM, POLARIZER, AND LIQUID-CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2009-06-18 US disclosed