SCHEMBL11987178

SCHEMBL11987178

CCOCCOc1ccc(C(C)(C)c2ccc(C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
PSMB1 P20618 1/20 0.45
PSMB5 P28074 1/20 0.45
PSMB2 P49721 1/20 0.45
NPC1 O15118 1/20 0.43
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
DRD2 P14416 2/20 0.42
DRD4 P21917 2/20 0.42
DRD3 P35462 2/20 0.42
ALDH1A1 P00352 3/20 0.41
TP53 P04637 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
TSHR P16473 2/20 0.41
CYP1A2 P05177 1/20 0.41
PPARG P37231 1/20 0.41
HIF1A Q16665 1/20 0.41
KDM4E B2RXH2 5/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4055644 0.93 SMN1; SMN2 (0.53) SMN1; SMN2PSMB1PSMB5PSMB2MEN1
SCHEMBL16747704 0.90 SMN1; SMN2 (0.50) SMN1; SMN2PSMB1PSMB5PSMB2MEN1
SCHEMBL82225 0.88 DRD2 (0.52) SMN1; SMN2MEN1KMT2ADRD2DRD4
SCHEMBL16451555 0.87 SMN1; SMN2 (0.64) SMN1; SMN2PSMB1PSMB5PSMB2MEN1
SCHEMBL12227907 0.87 SMN1; SMN2 (0.47) SMN1; SMN2PSMB1PSMB5PSMB2MEN1
SCHEMBL20872263 0.86 DRD2 (0.50) SMN1; SMN2MEN1KMT2ADRD2DRD4
SCHEMBL15138934 0.86 DRD2 (0.50) SMN1; SMN2MEN1KMT2ADRD2DRD4
SCHEMBL20372704 0.86 DRD2 (0.50) SMN1; SMN2MEN1KMT2ADRD2DRD4
SCHEMBL22172208 0.84 SMN1; SMN2 (0.51) SMN1; SMN2PSMB1PSMB5PSMB2NPC1
SCHEMBL12458332 0.84 SMN1; SMN2 (0.51) SMN1; SMN2PSMB1PSMB5PSMB2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8246737-B2 Cellulose ester optical film, polarizing plate and liquid crystal display using the same, method of manufacturing cellulose ester optical film, and copolymer KONICA MINOLTA OPTO, INC. (JP) 2012-08-21 US disclosed
US-20100069535-A1 Cellulose Ester Optical Film, Polarizing Plate and Liquid Crystal Display Using the Same, Method of Manufacturing Cellulose Ester Optical Film, and Copolymer. KONICA MINOLTA OPTO, INC. (JP) 2010-03-18 US disclosed