SCHEMBL11987362

SCHEMBL11987362

c1ccc2c(c1)oc1ccc(-c3ccc4c(c3)c3ccccc3n4-c3ccc(-n4c5ccccc5c5cc(-c6ccc7oc8ccccc8c7c6)ccc54)cc3)cc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAPT P10636 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
NPC1 O15118 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
RAB9A P51151 1/20 0.44
AHR P35869 2/20 0.40
PLA2G2A P14555 4/20 0.38
PLA2G4A P47712 4/20 0.38
CASP3 P42574 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11987361 0.98 KDM4E (0.44) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL24811820 0.98 KDM4E (0.44) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL16171583 0.98 KDM4E (0.44) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL16171578 0.97 KDM4E (0.43) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL22901605 0.96 KDM4E (0.46) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL24173830 0.96 KDM4E (0.42) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL24811819 0.96 KDM4E (0.50) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL21151548 0.96 KDM4E (0.46) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL21151187 0.96 KDM4E (0.46) KDM4EATML3MBTL1MAPTSMN1; SMN2
SCHEMBL21151189 0.96 KDM4E (0.46) KDM4EATML3MBTL1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9419231-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-08-16 US disclosed
US-9419231-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-08-16 US disclosed
US-20150034927-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-02-05 US disclosed
US-20150034927-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-02-05 US disclosed
US-20140027744-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-01-30 US disclosed
US-20140027744-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-01-30 US disclosed
US-8247089-B2 Organic electroluminescence element material, organic electroluminescence element, display device and lighting apparatus KONICA MINOLTA HOLDINGS, INC. (JP) 2012-08-21 US disclosed
US-8247089-B2 Organic electroluminescence element material, organic electroluminescence element, display device and lighting apparatus KONICA MINOLTA HOLDINGS, INC. (JP) 2012-08-21 US disclosed
US-20090302745-A1 Organic Electroluminescence Element Material, Organic Electroluminescence Element, Display Device and Lighting Apparatus KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-10 US disclosed
US-20090302745-A1 Organic Electroluminescence Element Material, Organic Electroluminescence Element, Display Device and Lighting Apparatus KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090302745-A1 Organic Electroluminescence Element Material, Organic Electroluminescence Element, Display Device and Lighting Apparatus LAGE3, ELAVL1, L1CAM KDM4E 1198/4885ATM 3816/4885L3MBTL1 86/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.