SCHEMBL11987366

SCHEMBL11987366

c1ccc2c(c1)oc1ccc(-c3ccc4c(c3)c3ccccc3n4-c3ccc4sc5ccc(-n6c7ccccc7c7cc(-c8ccc9oc%10ccccc%10c9c8)ccc76)cc5c4c3)cc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.36
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 2/20 0.36
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
KMT2A Q03164 2/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
AHR P35869 2/20 0.33
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
CHEK2 O96017 1/20 0.32
CASP3 P42574 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14867939 1.00 KDM4E (0.36) KDM4EMAPTSMN1; SMN2NPC1MEN1
SCHEMBL18266045 0.99 KDM4E (0.35) KDM4EMAPTSMN1; SMN2NPC1MEN1
SCHEMBL17248416 0.98 KDM4E (0.35) KDM4EMAPTSMN1; SMN2NPC1MEN1
SCHEMBL17248355 0.98 KDM4E (0.35) KDM4EMAPTSMN1; SMN2NPC1MEN1
SCHEMBL20633662 0.98 KDM4E (0.35) KDM4EMAPTSMN1; SMN2NPC1MEN1
SCHEMBL24728586 0.97 KDM4E (0.36) KDM4EMAPTSMN1; SMN2NPC1MEN1
SCHEMBL20706747 0.96 KDM4E (0.34) KDM4EMAPTSMN1; SMN2NPC1MEN1
SCHEMBL20706642 0.96 KDM4E (0.34) KDM4EMAPTSMN1; SMN2NPC1MEN1
SCHEMBL14649039 0.96 KDM4E (0.41) KDM4EMAPTSMN1; SMN2NPC1MEN1
SCHEMBL14867938 0.95 KDM4E (0.34) KDM4EMAPTSMN1; SMN2NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9419231-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-08-16 US disclosed
US-9419231-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-08-16 US disclosed
US-20150034927-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-02-05 US disclosed
US-20150034927-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-02-05 US disclosed
US-20140027744-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-01-30 US disclosed
US-20140027744-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-01-30 US disclosed
US-8247089-B2 Organic electroluminescence element material, organic electroluminescence element, display device and lighting apparatus KONICA MINOLTA HOLDINGS, INC. (JP) 2012-08-21 US disclosed
US-8247089-B2 Organic electroluminescence element material, organic electroluminescence element, display device and lighting apparatus KONICA MINOLTA HOLDINGS, INC. (JP) 2012-08-21 US disclosed
US-20090302745-A1 Organic Electroluminescence Element Material, Organic Electroluminescence Element, Display Device and Lighting Apparatus KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-10 US disclosed
US-20090302745-A1 Organic Electroluminescence Element Material, Organic Electroluminescence Element, Display Device and Lighting Apparatus KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090302745-A1 Organic Electroluminescence Element Material, Organic Electroluminescence Element, Display Device and Lighting Apparatus LAGE3, ELAVL1, L1CAM KDM4E 1198/4885MAPT 926/4885SMN1; SMN2 927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.