SCHEMBL11987979

SCHEMBL11987979

CC(C)(C)c1ccc2c(c1)c1cc(-c3ccc4c(c3)c3ccccc3n4-c3ccccc3)ccc1n2-c1ccc(-c2nnc(-c3ccccc3)o2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 8/20 0.43
▸ RAB9A P51151 8/20 0.43
▸ SMN1; SMN2 Q16637 5/20 0.43
▸ KDM4E B2RXH2 4/20 0.43
▸ HPGD P15428 4/20 0.43
▸ ALDH1A1 P00352 4/20 0.43
▸ S1PR1 P21453 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ CYP2D6 P10635 1/20 0.43
▸ ATM Q13315 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ POLB P06746 3/20 0.40
▸ EGFR P00533 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ NFKB1 P19838 1/20 0.40
▸ NFKB2 Q00653 1/20 0.40
▸ RELA Q04206 1/20 0.40
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11987984 0.95 S1PR1 (0.47) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL11987999 0.95 S1PR1 (0.47) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL13230198 0.94 S1PR1 (0.46) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL13230183 0.94 S1PR1 (0.46) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL12680716 0.94 S1PR1 (0.45) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL12680744 0.93 S1PR1 (0.47) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17948226 0.91 S1PR1 (0.46) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL17948222 0.91 S1PR1 (0.46) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL13230234 0.91 S1PR1 (0.49) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL13230232 0.91 S1PR1 (0.49) NPC1RAB9ASMN1; SMN2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530658-B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-10 — — US disclosed
US-8530658-B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-10 — — US disclosed
US-20120302751-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-11-29 — — US disclosed
US-20120302751-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-11-29 — — US disclosed
US-8247575-B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-08-21 — — US disclosed
US-8247575-B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-08-21 — — US disclosed
US-20100237339-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 — — US disclosed
US-20100237339-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 — — US disclosed
US-20100237773-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 — — US disclosed
US-20100237773-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237773-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SLC43A3, CRY1, VDAC3 NPC1 3646/4885RAB9A 2110/4885SMN1; SMN2 4473/4885
US-20120302751-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SLC43A3, CRY1, VDAC3 NPC1 3646/4885RAB9A 2110/4885SMN1; SMN2 4473/4885
US-20100237339-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SLC43A3, CRY1, VDAC3 NPC1 3646/4885RAB9A 2110/4885SMN1; SMN2 4473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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