Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11988810 | 0.91 | TSHR (0.36) | ABL1EPHX1METALDH1A1 | |
| SCHEMBL18473758 | 0.83 | EPHX1 (0.47) | EPHX1EPHX2ALDH1A1HTT | |
| SCHEMBL13126267 | 0.83 | EPHX1 (0.47) | EPHX1EPHX2ALDH1A1HTT | |
| SCHEMBL12462484 | 0.83 | EPHX1 (0.47) | EPHX1EPHX2ALDH1A1HTT | |
| SCHEMBL12374471 | 0.83 | FOLH1 (0.46) | ABL1 | |
| SCHEMBL13684302 | 0.82 | ABL1 (0.38) | ABL1EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15978635 | 0.82 | PAOX (0.39) | ABL1EPHX1CHEK1AURKACHUK | |
| SCHEMBL522870 | 0.82 | PAOX (0.39) | ABL1EPHX1CHEK1AURKACHUK | |
| SCHEMBL13997007 | 0.81 | EPHX1 (0.45) | EPHX1SMN1; SMN2EPHX2ALDH1A1HTT | |
| SCHEMBL13620528 | 0.81 | ABL1 (0.35) | ABL1EPHX1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247524-B2 | Preparation of supramolecular polymers containing quadruple hydrogen bonding units in the polymer backbone | SUPRAPOLIX B.V. (NL) | 2012-08-21 | — | — | US | disclosed |
| US-20110034641-A1 | PREPARATION OF SUPRAMOLECULAR POLYMERS CONTAINING QUADRUPLE HYDROGEN BONDING UNITS IN THE POLYMER BACKBONE | SUPRAPOLIX B.V. | 2011-02-10 | — | — | US | disclosed |