SCHEMBL12374471

SCHEMBL12374471

Cc1cc(=O)nc(NC(=O)NCCCCC(NC(=O)Nc2nc(=O)cc(C)[nH]2)C(=O)O)[nH]1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 19/20 0.46
▸ ABL1 P00519 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12374474 0.91 ABL1 (0.37) FOLH1ABL1
SCHEMBL21065266 0.88 TDP1 (0.43) —
SCHEMBL21065264 0.88 TDP1 (0.43) —
SCHEMBL12462486 0.88 FOLH1 (0.45) FOLH1
SCHEMBL23912468 0.88 FOLH1 (0.37) FOLH1
SCHEMBL12374495 0.86 FOLH1 (0.33) FOLH1ABL1
SCHEMBL12462224 0.86 SLC6A3 (0.35) —
SCHEMBL13684302 0.85 ABL1 (0.38) ABL1
SCHEMBL21065294 0.84 NAALAD2 (0.47) FOLH1
SCHEMBL12462485 0.84 NAALAD2 (0.47) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10813866-B2 Cosmetic composition, cosmetic treatment method, kit, and compound L'OREAL (FR) 2020-10-27 — — US disclosed
EP-2521530-B1 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, KIT, AND COMPOUND OREAL (FR) 2019-06-26 — — EP disclosed
US-8575341-B2 Cosmetic composition, cosmetic treatment method, and compound L'OREAL (FR) 2013-11-05 — — US disclosed
US-8575341-B2 Cosmetic composition, cosmetic treatment method, and compound L'OREAL (FR) 2013-11-05 — — US disclosed
US-20130017162-A1 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, KIT, AND COMPOUND L'OREAL (FR) 2013-01-17 — — US disclosed
US-20130017162-A1 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, KIT, AND COMPOUND L'OREAL (FR) 2013-01-17 — — US disclosed
US-20110189118-A1 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, AND COMPOUND L'OREAL (FR) 2011-08-04 — — US disclosed
US-20110189118-A1 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, AND COMPOUND L'OREAL (FR) 2011-08-04 — — US disclosed
WO-2011080494-A2 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, KIT, AND COMPOUND L'OREAL (FR) 2011-07-07 — — WO disclosed
WO-2010001041-A2 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, AND COMPOUND L'OREAL (FR) 2010-01-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130017162-A1 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, KIT, AND COMPOUND KRT18, KIT, TYR FOLH1 2171/4885ABL1 1039/4885
US-20110189118-A1 COSMETIC COMPOSITION, COSMETIC TREATMENT METHOD, AND COMPOUND KRT18, MC1R, C1R FOLH1 2378/4885ABL1 4705/4885
US-10813866-B2 Cosmetic composition, cosmetic treatment method, kit, and compound KRT18, KIT, TYR FOLH1 2171/4885ABL1 1039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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