Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10199553 | 0.84 | GLA (0.35) | TSHRKDM4EHTTATMGAA | |
| SCHEMBL812271 | 0.82 | ACACB (0.37) | ALDH1A1 | |
| SCHEMBL2349711 | 0.77 | ACACB (0.34) | ESR1ALDH1A1LMNA | |
| SCHEMBL18805640 | 0.76 | TSHR (0.38) | TSHRACHEKDM4EHTTATM | |
| SCHEMBL6113429 | 0.74 | ACACB (0.42) | KDM4EHTTATM | |
| SCHEMBL14395135 | 0.73 | BIRC5 (0.34) | KDM4EHTTATMESR1ESR2 | |
| SCHEMBL18786780 | 0.71 | ACHE (0.38) | TSHRACHEKDM4EHTTATM | |
| SCHEMBL2352633 | 0.70 | CNR1 (0.39) | ESR1ALDH1A1 | |
| SCHEMBL2355616 | 0.70 | ACACB (0.50) | — | |
| SCHEMBL11986867 | 0.70 | TSHR (0.39) | TSHRKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962599-B1 | INSECTICIDE COMPOUNDS WITH IMPROVED EFFECT | BAYER IP GMBH (DE) | 2016-03-16 | — | — | EP | disclosed |
| US-8247351-B2 | Insecticidal compositions having improved effect | BAYER CROPSCIENCE AG (DE) | 2012-08-21 | — | — | US | disclosed |
| US-8247351-B2 | Insecticidal compositions having improved effect | BAYER CROPSCIENCE AG (DE) | 2012-08-21 | — | — | US | disclosed |
| US-20110294783-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| US-20110294783-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| US-20090209513-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090209513-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| WO-2007068428-A2 | INSECTICIDAL COMPOSITIONS CONTAINING PHENYL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294783-A1 | Insecticidal Compositions Having Improved Effect | FASN, CYP51A1, PIKFYVE | TSHR 4115/4885ACHE 145/4885KDM4E 367/4885 |
| US-20090209513-A1 | Insecticidal Compositions Having Improved Effect | PTEN, PIK3CG, PIK3CD | TSHR 4566/4885ACHE 19/4885KDM4E 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.