SCHEMBL11989404

SCHEMBL11989404

CCN(CCO)CCCNC(=O)OC(C)(C)C

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
MEN1 O00255 1/20 0.50
GAA P10253 1/20 0.50
KMT2A Q03164 1/20 0.50
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
CA12 O43570 7/20 0.44
CA1 P00915 7/20 0.44
CA2 P00918 6/20 0.44
CA9 Q16790 6/20 0.44
DRD2 P14416 3/20 0.43
ALDH1A1 P00352 1/20 0.42
CA14 Q9ULX7 2/20 0.41
ACHE P22303 1/20 0.39
CA7 P43166 1/20 0.39
EPHX1 P07099 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15889841 0.92 TDP1 (0.54) TDP1MEN1GAAKMT2AMAOA
SCHEMBL19123153 0.92 TDP1 (0.67) TDP1MEN1GAAKMT2AMAOA
SCHEMBL9773831 0.92 TDP1 (0.67) TDP1MEN1GAAKMT2AMAOA
SCHEMBL28425597 0.92 TDP1 (0.62) TDP1MEN1GAAKMT2AMAOA
SCHEMBL25963707 0.90 TDP1 (0.65) TDP1MEN1GAAKMT2AMAOA
SCHEMBL19243536 0.88 TDP1 (0.54) TDP1MEN1GAAKMT2AMAOA
SCHEMBL15610483 0.87 TDP1 (0.68) TDP1MEN1GAAKMT2AMAOA
SCHEMBL31040402 0.85 CA14 (0.60) TDP1MEN1GAAKMT2AMAOA
SCHEMBL270450 0.85 TDP1 (0.51) TDP1MEN1GAAKMT2AMAOA
SCHEMBL1206172 0.84 TDP1 (0.60) TDP1MEN1GAAKMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8247493-B2 Long acting formulation of biopharmaceutical POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2012-08-21 US disclosed
US-8247493-B2 Long acting formulation of biopharmaceutical POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2012-08-21 US disclosed
US-20110111477-A9 LONG ACTING FORMULATION OF BIOPHARMACEUTICAL POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2011-05-12 US disclosed
US-20110111477-A9 LONG ACTING FORMULATION OF BIOPHARMACEUTICAL POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2011-05-12 US disclosed
US-20100261245-A1 LONG ACTING FORMULATION OF BIOPHARMACEUTICAL POSCO (KR) 2010-10-14 US disclosed
US-20100261245-A1 LONG ACTING FORMULATION OF BIOPHARMACEUTICAL POSCO (KR) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261245-A1 LONG ACTING FORMULATION OF BIOPHARMACEUTICAL VEGFA, CD44, HACD3 TDP1 1341/4885MEN1 3626/4885GAA 336/4885
US-20110111477-A9 LONG ACTING FORMULATION OF BIOPHARMACEUTICAL VEGFA, CD44, HACD3 TDP1 1341/4885MEN1 3626/4885GAA 336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.