Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15132643 | 1.00 | ACHE (0.76) | ACHEABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL16526224 | 1.00 | ACHE (0.76) | ACHEABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL14201320 | 0.95 | ACHE (0.85) | ACHEEPHX1 | |
| SCHEMBL10299296 | 0.91 | ACHE (0.63) | ACHEEPHX1 | |
| SCHEMBL16544803 | 0.89 | ACHE (0.58) | ACHEABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL28158857 | 0.88 | ACHE (0.72) | ACHEEPHX1 | |
| SCHEMBL8588602 | 0.87 | ACHE (0.60) | ACHE | |
| SCHEMBL19107903 | 0.87 | ACHE (0.68) | ACHEEPHX1 | |
| SCHEMBL19107899 | 0.87 | ACHE (0.68) | ACHEEPHX1 | |
| SCHEMBL5248138 | 0.86 | ACHE (0.80) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247493-B2 | Long acting formulation of biopharmaceutical | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2012-08-21 | — | — | US | disclosed |