SCHEMBL119910

SCHEMBL119910

O=C(O)C[C@H](CCCCNC(=O)OCC1c2ccccc2-c2ccccc21)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.67
CASP3 P42574 4/20 0.53
MDM4 O15151 1/20 0.43
TP53 P04637 1/20 0.43
MDM2 Q00987 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29397881 0.91 KMT2A (0.56) KMT2ACASP3MDM2
SCHEMBL4600617 0.91 KMT2A (0.56) KMT2ACASP3MDM2
SCHEMBL29483213 0.91 KMT2A (0.56) KMT2ACASP3MDM2
SCHEMBL4600619 0.91 KMT2A (0.56) KMT2ACASP3MDM2
SCHEMBL13775067 0.89 KMT2A (0.63) KMT2ACASP3MDM4TP53
SCHEMBL25261537 0.88 KMT2A (0.54) KMT2ACASP3MDM2
SCHEMBL25292322 0.88 KMT2A (0.54) KMT2ACASP3MDM2
SCHEMBL30497284 0.88 KMT2A (0.54) KMT2ACASP3MDM2
SCHEMBL30678656 0.88 CASP3 (0.53) KMT2ACASP3MDM4TP53MDM2
SCHEMBL28413990 0.87 CASP3 (0.55) KMT2ACASP3MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed