Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 6/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.30 |
| ▸ | CKS1B | P61024 | 1/20 | 0.30 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11992196 | 0.97 | AVPR2 (0.34) | TOP1AVPR2AVPR1APIM1PIM2 | |
| SCHEMBL11992182 | 0.90 | TOP1 (0.36) | TOP1PIM1PIM2BRD4PARP1 | |
| SCHEMBL11992184 | 0.88 | CYP17A1 (0.36) | TOP1PIM1PIM2BRD4CYP3A4 | |
| SCHEMBL11992190 | 0.88 | BRD4 (0.39) | TOP1PIM1PIM2BRD4PARP1 | |
| SCHEMBL11992193 | 0.88 | TOP1 (0.39) | TOP1PIM1PIM2PARP1CYP3A4 | |
| SCHEMBL11992185 | 0.88 | TOP1 (0.39) | TOP1PIM1PIM2PARP1CYP3A4 | |
| SCHEMBL11992195 | 0.87 | BRD4 (0.37) | TOP1PIM1PIM2BRD4PARP1 | |
| SCHEMBL11992310 | 0.87 | TOP1 (0.37) | TOP1PIM1PIM2BRD4PARP1 | |
| SCHEMBL11992177 | 0.87 | TOP1 (0.37) | TOP1PIM1PIM2BRD4CYP3A4 | |
| SCHEMBL11992172 | 0.87 | TOP1 (0.36) | TOP1PIM1PIM2BRD4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273002-B2 | Benzo[k]fluoranthene derivative and organic electroluminescence device containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-03-01 | — | — | US | disclosed |
| US-9273002-B2 | Benzo[k]fluoranthene derivative and organic electroluminescence device containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-03-01 | — | — | US | disclosed |
| US-20120211743-A1 | BENZO[k]FLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-08-23 | — | — | US | disclosed |
| US-20120211743-A1 | BENZO[k]FLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120211743-A1 | BENZO[k]FLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME | KCNJ2, KCNE1, KCNK2 | TOP1 2070/4885AVPR2 1814/4885AVPR1A 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.