SCHEMBL11996075

SCHEMBL11996075

C=CC(=O)OCCOCCOC(=O)CC(C)=O

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.68
ALDH1A1 P00352 6/20 0.68
TP53 P04637 3/20 0.68
HIF1A Q16665 3/20 0.68
HSD17B10 Q99714 1/20 0.68
THRB P10828 4/20 0.51
HPGD P15428 1/20 0.47
CYP3A4 P08684 2/20 0.47
MGAM O43451 2/20 0.39
GAA P10253 2/20 0.39
SI P14410 2/20 0.39
MGAM2 Q2M2H8 2/20 0.39
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12394965 1.00 TSHR (0.68) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12394981 1.00 TSHR (0.68) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL218670 0.94 TSHR (0.57) TSHRALDH1A1TP53HIF1AHSD17B10
Isopropyl Alcohol SCHEMBL28381086 0.88 TSHR (0.50) TSHRALDH1A1TP53HIF1AHSD17B10
Acetoacetic Acid SCHEMBL21044399 0.88 TSHR (0.50) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL295847 0.87 TSHR (0.59) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL271812 0.87 TSHR (0.64) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL9923834 0.86 TSHR (0.68) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10899111 0.85 TSHR (0.47) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL11408466 0.84 GAA (0.52) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9234256-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2016-01-12 US disclosed
US-9234256-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2016-01-12 US disclosed
US-8652335-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2014-02-18 US disclosed
US-8652335-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2014-02-18 US disclosed
US-20120211439-A1 SCAVENGER SUPPORTS AND THE USE THEREOF IN A PROCESS FOR THE EXTRACTION OF METALS JOHNSON MATTHEY FINLAND OY (FI) 2012-08-23 US disclosed
US-20120211439-A1 SCAVENGER SUPPORTS AND THE USE THEREOF IN A PROCESS FOR THE EXTRACTION OF METALS JOHNSON MATTHEY FINLAND OY (FI) 2012-08-23 US disclosed
US-20110168044-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-07-14 US disclosed
US-20090023604-A1 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2009-01-22 US disclosed
US-20090023604-A1 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2009-01-22 US disclosed
EP-1769094-B1 SCAVENGER SUPPORTS WITH AMINO-FUNCTIONALISED PENDANT KETOESTER OR KETOAMIDE GROUPS FOR REMOVING METALS FROM SOLUTIONS REAXA LTD (GB) 2008-12-10 EP disclosed
EP-1299429-B1 SCAVENGER RESIN AND PROCESSES FOR THE USE THEREOF REAXA LTD (GB) 2007-03-07 EP disclosed