SCHEMBL218670

SCHEMBL218670

C=CC(=O)OCCOC(=O)CC(C)=O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.57
ALDH1A1 P00352 5/20 0.57
TP53 P04637 3/20 0.57
HIF1A Q16665 3/20 0.57
HSD17B10 Q99714 1/20 0.57
CYP3A4 P08684 2/20 0.52
HPGD P15428 1/20 0.52
THRB P10828 4/20 0.47
MGAM O43451 2/20 0.43
GAA P10253 2/20 0.43
SI P14410 2/20 0.43
MGAM2 Q2M2H8 2/20 0.43
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ATM Q13315 1/20 0.32
DGKA P23743 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12394965 0.94 TSHR (0.68) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12394981 0.94 TSHR (0.68) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL11996075 0.94 TSHR (0.68) TSHRALDH1A1TP53HIF1AHSD17B10
Isopropyl Alcohol SCHEMBL28381086 0.93 TSHR (0.50) TSHRALDH1A1TP53HIF1AHSD17B10
Acetoacetic Acid SCHEMBL21044399 0.93 TSHR (0.50) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL295847 0.92 TSHR (0.59) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL271812 0.92 TSHR (0.64) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL9923834 0.91 TSHR (0.68) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10899111 0.90 TSHR (0.47) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL1150833 0.87 TSHR (0.67) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3861 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4701996-A1 AQUEOUS DISPERSION FOR CEMENTITIOUS WATERPROOFING MATERIAL AND THE USE THEREOF BASF SE (DE) 2026-03-04 EP claimed
US-12497475-B2 Aqueous polymer composition and method of preparing thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2025-12-16 US claimed
US-12480001-B2 Powder paint composition which can be redispersed in water WACKER CHEMIE AG (DE) 2025-11-25 US claimed
EP-4642823-A1 AQUEOUS POLYMER DISPERSION AND COATING COMPOSITION Dow Global Technologies LLC (US) 2025-11-05 EP claimed
US-12421342-B2 Crosslinkable reactive silicone organic copolymers dispersions WACKER CHEMIE AG (DE) 2025-09-23 US claimed
EP-4225817-B1 AQUEOUS POLYMER COMPOSITION AND METHOD OF PREPARING THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-16 EP claimed
US-20250215145-A1 POLYURETHANE COMPOSITIONS, COMPOSITE MATERIALS PREPARED WITH SAME AND PREPARATION METHODS THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-03 US claimed
CN-120072418-A Preparation method of anti-fouling wire 东莞市杰讯电子科技有限公司 2025-05-30 CN claimed
CN-119931442-A Mold-resistant water-based paint, preparation method thereof and application thereof in high-humidity environment 山东祥号新材料科技有限公司 2025-05-06 CN claimed
CN-119731221-A Self-curable and foamable two-component acrylic adhesive 科学把手粘合剂公司 2025-03-28 CN claimed
EP-0407667-A1 Pressure-sensitive adhesives and manufactured articles ROHM AND HAAS COMPANY (US) 1991-01-16 EP claimed
US-4946932-A Water-dispersible polyester blends EASTMAN KODAK COMPANY (US) 1990-08-07 US claimed
EP-0372804-A2 Ambient temperature curing polymer compositions RHONE-POULENC CHEMICALS LIMITED (GB) 1990-06-13 EP claimed
US-4908403-A High cohesive strength UNION OIL OF CALIFORNIA (US) 1990-03-13 US claimed
US-4906684-A Ambient temperature curing polymer compositions containing acetoacetoxyethyl methacrylate, glycidyl methacrylate and a polymerizable acid RTZ CHEMICALS, LTD. (GB) 1990-03-06 US claimed
EP-0340653-A2 Kit for electrophoresis gel medium EASTMAN KODAK COMPANY (US) 1989-11-08 EP claimed
EP-0296286-A1 Pressure sensitive adhesives and adhesive articles UNION OIL COMPANY OF CALIFORNIA (US) 1988-12-28 EP claimed
US-4759983-A Conjugated diolefin polymer, olefin ester interpolymers, olefinically unsaturated carboxylic acid ester polymer, alkenyl ether polymer and combinations UNION OIL COMPANY OF CALIFORNIA (US) 1988-07-26 US claimed
EP-0244997-A2 Pressure sensitive adhesives and manufactured articles UNION OIL COMPANY OF CALIFORNIA (US) 1987-11-11 EP claimed
US-4284708-A ACID POLYMER LAYER AND RETARDER LAYER; NEUTRALIZATION AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1981-08-18 US claimed