SCHEMBL11996086

SCHEMBL11996086

Cc1ccc(Cn2c(=O)oc(=O)c3ccccc32)cc1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.69
P2RX4 Q99571 2/20 0.66
MIF P14174 3/20 0.55
CD74 P04233 1/20 0.55
KDM4E B2RXH2 3/20 0.53
GAA P10253 1/20 0.53
HSD17B10 Q99714 1/20 0.53
RECQL P46063 1/20 0.52
MAPK10 P53779 1/20 0.52
TSHR P16473 2/20 0.52
IDO1 P14902 1/20 0.51
TP53 P04637 1/20 0.49
KMT2A Q03164 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
MAPK1 P28482 1/20 0.48
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1522607 0.88 MIF (0.66) ALDH1A1P2RX4MIFCD74KDM4E
SCHEMBL9047870 0.87 IDO1 (0.68) ALDH1A1P2RX4MIFKDM4EMAPK10
SCHEMBL5308662 0.85 NPC1 (0.55) ALDH1A1P2RX4MIFIDO1TP53
SCHEMBL368418 0.85 MIF (0.55) ALDH1A1P2RX4MIFCD74TSHR
SCHEMBL2860677 0.85 P2RX4 (0.68) ALDH1A1P2RX4MIFGAAIDO1
SCHEMBL5308571 0.85 MEN1 (0.51) ALDH1A1P2RX4MIFCD74IDO1
SCHEMBL5124040 0.83 MIF (0.71) ALDH1A1P2RX4MIFCD74TP53
SCHEMBL1716066 0.82 MIF (0.51) ALDH1A1P2RX4MIFCD74KDM4E
SCHEMBL10036738 0.82 IDO1 (0.55) ALDH1A1P2RX4MIFCD74TSHR
SCHEMBL1715052 0.82 IDO1 (0.48) ALDH1A1P2RX4MIFIDO1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9234256-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2016-01-12 US disclosed
US-9234256-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2016-01-12 US disclosed
US-8652335-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2014-02-18 US disclosed
US-20120211439-A1 SCAVENGER SUPPORTS AND THE USE THEREOF IN A PROCESS FOR THE EXTRACTION OF METALS JOHNSON MATTHEY FINLAND OY (FI) 2012-08-23 US disclosed
US-20090025874-A1 Novel Adducts Useful As Cure Components For Anaerobic Curable Compositions HENKEL CORPORATION (US) 2009-01-29 US disclosed
US-20090023604-A1 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2009-01-22 US disclosed
US-20090023604-A1 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2009-01-22 US disclosed