Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 3/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | CD74 | P04233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996086 | 0.85 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1IDO1MIF | |
| SCHEMBL1522607 | 0.84 | MIF (0.66) | MEN1KMT2AALDH1A1IDO1MIF | |
| SCHEMBL9047870 | 0.83 | IDO1 (0.68) | MEN1KMT2AALDH1A1IDO1MIF | |
| SCHEMBL368418 | 0.82 | MIF (0.55) | MEN1KMT2AALDH1A1IDO1MIF | |
| SCHEMBL5308662 | 0.82 | NPC1 (0.55) | MEN1KMT2AALDH1A1IDO1MIF | |
| SCHEMBL2860677 | 0.81 | P2RX4 (0.68) | MEN1KMT2AALDH1A1IDO1MIF | |
| SCHEMBL30616071 | 0.81 | CYP19A1 (0.63) | MEN1KMT2AMETAP2P2RX4TP53 | |
| SCHEMBL22166644 | 0.81 | CYP19A1 (0.63) | MEN1KMT2AMETAP2P2RX4TP53 | |
| SCHEMBL1522968 | 0.80 | PTGDR2 (0.45) | MEN1KMT2AALDH1A1METAP2TP53 | |
| SCHEMBL1716066 | 0.79 | MIF (0.51) | MEN1KMT2AALDH1A1IDO1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |