Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.73 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.73 |
| ▸ | ACP1 | P24666 | 6/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996404 | 1.00 | PTPN1 (0.73) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL3891157 | 0.89 | PTPN1 (0.59) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL3891749 | 0.89 | PTPN1 (0.59) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL3891738 | 0.89 | PTPN1 (0.59) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL3890248 | 0.84 | PTPN1 (0.55) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL3890244 | 0.84 | PTPN1 (0.55) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL17309393 | 0.84 | CA9 (0.60) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL19481523 | 0.84 | CA9 (0.60) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL12013726 | 0.84 | CA9 (0.56) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL3891123 | 0.84 | CA9 (0.56) | PTPN1AKR1B1ACP1CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252794-B2 | Composition for regenerative treatment of cartilage disease | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-08-28 | — | — | US | claimed |
| US-8252940-B2 | 5-substituted-2-imino-thiazolidinone compounds and their use as inhibitors of bacterial infection | UNIVERSITY OF WASHINGTON (US) | 2012-08-28 | — | — | US | disclosed |