Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | ACP1 | P24666 | 5/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.57 |
| ▸ | TCF4 | P15884 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891749 | 1.00 | PTPN1 (0.59) | PTPN1AKR1B1ACP1CTNNB1TCF4 | |
| SCHEMBL3891029 | 0.90 | PTPN1 (0.53) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL3891039 | 0.90 | PTPN1 (0.53) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL11996404 | 0.89 | PTPN1 (0.73) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL11996403 | 0.89 | PTPN1 (0.73) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL3897058 | 0.88 | PTPN1 (0.52) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL3897051 | 0.88 | PTPN1 (0.52) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL3891123 | 0.88 | CA9 (0.56) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL12013726 | 0.88 | CA9 (0.56) | PTPN1AKR1B1ACP1CA9MEN1 | |
| SCHEMBL3891119 | 0.88 | CA9 (0.56) | PTPN1AKR1B1ACP1CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252940-B2 | 5-substituted-2-imino-thiazolidinone compounds and their use as inhibitors of bacterial infection | UNIVERSITY OF WASHINGTON (US) | 2012-08-28 | — | — | US | disclosed |
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |