Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.43 |
| ▸ | ACP1 | P24666 | 9/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996414 | 1.00 | PTGES (0.43) | PTGESPTPN1ACP1PTPN2FAAH | |
| SCHEMBL11996415 | 1.00 | PTGES (0.43) | PTGESPTPN1ACP1PTPN2FAAH | |
| SCHEMBL11996411 | 0.92 | PTGES (0.47) | PTGESPTPN1ACP1PTPN2FAAH | |
| SCHEMBL3892767 | 0.92 | PTGES (0.47) | PTGESPTPN1ACP1PTPN2FAAH | |
| SCHEMBL11996412 | 0.92 | PTGES (0.47) | PTGESPTPN1ACP1PTPN2FAAH | |
| SCHEMBL11996392 | 0.86 | PTPN1 (0.46) | PTGESPTPN1ACP1PTPN2FAAH | |
| SCHEMBL11996391 | 0.86 | PTPN1 (0.46) | PTGESPTPN1ACP1PTPN2FAAH | |
| SCHEMBL3955366 | 0.86 | PTPN1 (0.46) | PTGESPTPN1ACP1PTPN2FAAH | |
| SCHEMBL3893584 | 0.84 | PTGES (0.47) | PTGESPTPN1ACP1PTPN2FAAH | |
| SCHEMBL3893586 | 0.84 | PTGES (0.47) | PTGESPTPN1ACP1PTPN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252940-B2 | 5-substituted-2-imino-thiazolidinone compounds and their use as inhibitors of bacterial infection | UNIVERSITY OF WASHINGTON (US) | 2012-08-28 | — | — | US | disclosed |