Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746369 | 0.75 | POLA1 (0.59) | KMT2ADHFR | |
| SCHEMBL7036447 | 0.74 | KMT2A (0.64) | KMT2AABL1RIN1 | |
| SCHEMBL6783250 | 0.72 | TP53 (0.73) | — | |
| SCHEMBL8146595 | 0.71 | — | — | |
| SCHEMBL9543202 | 0.70 | BACE1 (0.57) | KMT2AABL1RIN1 | |
| SCHEMBL9543645 | 0.68 | ABL1 (0.56) | KMT2AABL1RIN1 | |
| SCHEMBL9543525 | 0.68 | ABL1 (0.59) | KMT2AABL1RIN1 | |
| SCHEMBL10981661 | 0.67 | ABL1 (0.51) | KMT2AABL1RIN1 | |
| SCHEMBL26805115 | 0.67 | MEN1 (0.48) | KMT2A | |
| SCHEMBL7698417 | 0.67 | UNG (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401829-B1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX INC (US) | 2012-08-22 | — | — | EP | disclosed |