Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15346534 | 0.86 | HTT (0.79) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL9340146 | 0.86 | HTT (0.79) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL9874334 | 0.86 | HTT (0.79) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL7064126 | 0.86 | TGM2 (0.63) | TGM2HTTFAAHLMNASMN1; SMN2 | |
| SCHEMBL7064121 | 0.86 | TGM2 (0.63) | TGM2HTTFAAHLMNASMN1; SMN2 | |
| SCHEMBL6444628 | 0.85 | TGM2 (0.69) | TGM2HTTFAAHLMNASMN1; SMN2 | |
| SCHEMBL8811162 | 0.85 | TGM2 (0.69) | TGM2HTTFAAHLMNASMN1; SMN2 | |
| SCHEMBL8988858 | 0.85 | TGM2 (0.69) | TGM2HTTFAAHLMNASMN1; SMN2 | |
| SCHEMBL29951855 | 0.85 | TGM2 (0.69) | TGM2HTTFAAHLMNASMN1; SMN2 | |
| SCHEMBL6523296 | 0.85 | TGM2 (0.62) | TGM2HTTFAAHLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2489655-A1 | PROCESS FOR PREPARATION OF DIETHYLENETRIAMINEPENTAACETIC ACID DERIVATIVES, AND DIETHYLENETRIAMINEPENTAACETIC ACID DERIVATIVES | The University of Tokushima (JP) | 2012-08-22 | — | — | EP | disclosed |