Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | BRD4 | O60885 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12667143 | 1.00 | MAPT (0.66) | MAPTBRD4SMN1; SMN2POLBLMNA | |
| SCHEMBL28566909 | 0.87 | BRD4 (0.57) | MAPTBRD4SMN1; SMN2POLBLMNA | |
| SCHEMBL28566910 | 0.87 | BRD4 (0.57) | MAPTBRD4SMN1; SMN2POLBLMNA | |
| SCHEMBL11997282 | 0.85 | TSHR (0.60) | MAPTBRD4SMN1; SMN2POLBLMNA | |
| SCHEMBL563682 | 0.85 | BRD4 (0.55) | MAPTBRD4SMN1; SMN2POLBLMNA | |
| SCHEMBL5011683 | 0.85 | BRD4 (0.55) | MAPTBRD4SMN1; SMN2POLBLMNA | |
| SCHEMBL19295649 | 0.82 | BRD4 (0.55) | MAPTBRD4SMN1; SMN2POLBGAA | |
| SCHEMBL15041968 | 0.82 | BRD4 (0.55) | MAPTBRD4SMN1; SMN2POLBGAA | |
| SCHEMBL12206410 | 0.82 | BRD4 (0.51) | MAPTBRD4SMN1; SMN2POLBLMNA | |
| SCHEMBL15042063 | 0.81 | MAPT (0.60) | MAPTBRD4SMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734180-B1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES | OREAL (FR) | 2021-03-31 | — | — | EP | disclosed |
| US-10479868-B2 | Polymeric stabilizing formulations | NANO PRECISION MEDICAL, INC. (US) | 2019-11-19 | — | — | US | disclosed |
| US-20170274089-A1 | POLYMERIC STABILIZING FORMULATIONS | NANO PRECISION MEDICAL, INC. | 2017-09-28 | — | — | US | disclosed |
| EP-2579841-B1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | ORÉAL L (FR) | 2016-09-14 | — | — | EP | disclosed |
| US-20140294743-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES | L'OREAL (FR) | 2014-10-02 | — | — | US | disclosed |
| US-20140294743-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES | L'OREAL (FR) | 2014-10-02 | — | — | US | disclosed |
| US-8771376-B2 | Composition comprising at least one 2-pyrrolidone functionalized with an ester or amide radical, and at least one pigment or direct dye, for dyeing keratin materials | L'OREAL (FR) | 2014-07-08 | — | — | US | disclosed |
| US-8771376-B2 | Composition comprising at least one 2-pyrrolidone functionalized with an ester or amide radical, and at least one pigment or direct dye, for dyeing keratin materials | L'OREAL (FR) | 2014-07-08 | — | — | US | disclosed |
| US-20130152314-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | L'OREAL (FR) | 2013-06-20 | — | — | US | disclosed |
| US-20130152314-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | L'OREAL (FR) | 2013-06-20 | — | — | US | disclosed |
| US-20100183530-A1 | Cosmetic compositions comprising 4-carboxy-2-pyrrolidinone esters and triazine lipophilic UV-screening agents | L'OREAL (FR) | 2010-07-22 | — | — | US | disclosed |
| US-20100183529-A1 | Cosmetic compositions comprising photostabilized dibenzoylmethane compounds and 2-pyrrolidinone-4- carboxy esters | L'OREAL (FR) | 2010-07-22 | — | — | US | disclosed |
| US-20100183529-A1 | Cosmetic compositions comprising photostabilized dibenzoylmethane compounds and 2-pyrrolidinone-4- carboxy esters | L'OREAL (FR) | 2010-07-22 | — | — | US | disclosed |
| US-20100183530-A1 | Cosmetic compositions comprising 4-carboxy-2-pyrrolidinone esters and triazine lipophilic UV-screening agents | L'OREAL (FR) | 2010-07-22 | — | — | US | disclosed |
| US-20100143276-A1 | Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions | L'OREAL (FR) | 2010-06-10 | — | — | US | disclosed |
| US-20100143276-A1 | Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions | L'OREAL (FR) | 2010-06-10 | — | — | US | disclosed |
| EP-2193784-A1 | Cosmetic compositions containing an ester derivative of 2-pyrrolidinone 4-carboxy and a lipophilic triazine filter, with use of said derivative as a solvent of a lipophilic triazine filter | L'OREAL (FR) | 2010-06-09 | — | — | EP | disclosed |
| EP-2193783-A1 | Use of an ester derived from 4-carboxy-2-pyrrolidinone as a solvent in cosmetic compositions; cosmetic compositions containing same | L'Oreal (FR) | 2010-06-09 | — | — | EP | disclosed |
| EP-2193782-A1 | Cosmetic composition comprising a dibenzoylmethane derivative and a 2-pyrrolidinone-4-carboxy ester compound; method for the photostabilization of the dibenzoylmethane derivative | L'Oreal (FR) | 2010-06-09 | — | — | EP | disclosed |
| US-4071530-A | Pyrrolidones and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170274089-A1 | POLYMERIC STABILIZING FORMULATIONS | IAPP, INSR, GPR119 | MAPT 1172/4885BRD4 3584/4885SMN1; SMN2 1239/4885 |
| US-10479868-B2 | Polymeric stabilizing formulations | IAPP, INSR, GPR119 | MAPT 1172/4885BRD4 3584/4885SMN1; SMN2 1239/4885 |
| US-20130152314-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | KRT18, ADH1A, ADH5 | MAPT 254/4885BRD4 446/4885SMN1; SMN2 4418/4885 |
| US-20100183530-A1 | Cosmetic compositions comprising 4-carboxy-2-pyrrolidinone esters and triazine lipophilic UV-screening agents | TYR, PAH, C1S | MAPT 2496/4885BRD4 674/4885SMN1; SMN2 4643/4885 |
| US-20100143276-A1 | Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions | FASN, ALOX12, PAH | MAPT 3479/4885BRD4 1020/4885SMN1; SMN2 3473/4885 |
| US-20140294743-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES | KRT18, LAGE3, TYR | MAPT 611/4885BRD4 2467/4885SMN1; SMN2 4825/4885 |
| US-20100183529-A1 | Cosmetic compositions comprising photostabilized dibenzoylmethane compounds and 2-pyrrolidinone-4- carboxy esters | CYP1B1, C1S, DDT | MAPT 1989/4885BRD4 371/4885SMN1; SMN2 4060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.