Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Hydrogen Phosphonate SCHEMBL3975323 | 0.83 | TSHR (0.32) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| Hydrogen Peroxide SCHEMBL18614730 | 0.81 | — | — | |
| SCHEMBL4635 | 0.80 | — | — | |
| SCHEMBL907968 | 0.80 | TSHR (0.44) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL29399686 | 0.80 | — | — | |
| SCHEMBL2487739 | 0.80 | — | — | |
| Phosphonic Acid SCHEMBL11825340 | 0.79 | ACE2 (0.50) | CA1FDPSLMNAACE2TP53 | |
| Phosphonic Acid SCHEMBL9263507 | 0.79 | ACE2 (0.50) | CA1FDPSLMNAACE2TP53 | |
| Phosphonic Acid SCHEMBL11315930 | 0.79 | ACE2 (0.50) | CA1FDPSLMNAACE2TP53 | |
| Acetone SCHEMBL290188 | 0.79 | TDP1 (0.46) | TSHRCHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101070506-B | Gear fluids | AFTON CHEMICAL CORP | 2011-04-20 | — | — | CN | disclosed |
| US-20110028604-A1 | FLAME-RETARDANT, CURABLE MOULDING MATERIALS | LANXESS DEUTSCHLAND GMBH (DE) | 2011-02-03 | — | — | US | disclosed |
| US-20080210914-A1 | Halogen free, low filler content, maintains viscosity; neutralization product of ethylenediamine and orthophosphoric acid combined with additional phosphorus and nitrogen compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2008-09-04 | — | — | US | disclosed |
| US-7410935-B2 | Gear fluids | AFTON CHEMICAL CORPORATION (US) | 2008-08-12 | — | — | US | disclosed |
| CN-101096610-A | A gear additive composition | AFTON CHEMICAL CORP (US) | 2008-01-02 | — | — | CN | disclosed |
| CN-101070506-A | Gear fluids | AFTON CHEMICAL CORP (US) | 2007-11-14 | — | — | CN | disclosed |
| EP-1840194-A1 | Gear fluids | Afton Chemical Corporation (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20070225182-A1 | Gear fluids | AFTON CHEMICAL CORPORATION | 2007-09-27 | — | — | US | disclosed |
| EP-1785475-A1 | A gear additive composition | Afton Chemical Corporation (US) | 2007-05-16 | — | — | EP | disclosed |
| US-20070105729-A1 | Gear additive composition | AFTON CHEMICAL CORPORATION | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225182-A1 | Gear fluids | PHOSPHO1, F12, PIK3CA | TSHR 2476/4885CHRM1 355/4885AKR1A1 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.