Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2827965 | 0.91 | TDP1 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Acetic Acid SCHEMBL6847761 | 0.88 | TDP1 (0.48) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Bicarbonate SCHEMBL7424110 | 0.88 | HDAC1 (0.52) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Bicarbonate SCHEMBL9490608 | 0.88 | HDAC1 (0.52) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Bicarbonate SCHEMBL14245001 | 0.88 | HDAC1 (0.52) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Acetic Acid SCHEMBL1588800 | 0.86 | TDP1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Acetic Acid SCHEMBL5762920 | 0.86 | TDP1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Acetic Acid SCHEMBL4482555 | 0.86 | TDP1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Bicarbonate SCHEMBL28420339 | 0.85 | CHRM1 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Ethyl Acetate SCHEMBL27881618 | 0.83 | ALDH1A1 (0.61) | TDP1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551839-B | Heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2024-06-04 | — | — | CN | disclosed |
| US-20240158375-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2024-05-16 | — | — | US | disclosed |
| WO-2023250518-A2 | CATALYST FOR POLYMERIZATION OF CYCLIC ETHER AND CYCLIC ESTER MONOMERS AND THE RESULTING POLYMERS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-12-28 | — | — | WO | disclosed |
| US-20230348517-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2023-11-02 | — | — | US | disclosed |
| CN-116940570-A | Compounds and methods for treating ocular disorders | 阿祖拉眼科有限公司 | 2023-10-24 | — | — | CN | disclosed |
| EP-4232149-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | AZURA OPHTHALMICS LTD (IL) | 2023-08-30 | — | — | EP | disclosed |
| EP-4232458-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | AZURA OPHTHALMICS LTD (IL) | 2023-08-30 | — | — | EP | disclosed |
| CN-116670116-A | Compounds and methods for treating ocular disorders | 阿祖拉眼科有限公司 | 2023-08-29 | — | — | CN | disclosed |
| US-11643429-B2 | Compounds and methods for the treatment of ocular disorders | Azura Ophthalmics Ltd. (IL) | 2023-05-09 | — | — | US | disclosed |
| WO-2023067387-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF DERMAL AND OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2023-04-27 | — | — | WO | disclosed |
| US-5977105-A | Compounds | ASTRA PHARMAEUTICALS LTD. (GB) | 1999-11-02 | — | — | US | disclosed |
| WO-1999005143-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-02-04 | — | — | WO | disclosed |
| EP-0454365-B1 | Pressure sensitive adhesive comprising tacky microspheres and macromonomer-containing binder copolymer | MINNESOTA MINING & MFG (US) | 1996-08-14 | — | — | EP | disclosed |
| US-5502108-A | SOLID ACRYLATE POLYMER SPHERES AND BINDERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0419020-B1 | Pressure-sensitive adhesive comprising hollow tacky microspheres and macromonomer-containing binder copolymer | MINNESOTA MINING & MFG (US) | 1995-01-25 | — | — | EP | disclosed |
| US-5215818-A | Pressure-sensitive adhesive comprising solid tacky microspheres and macromonomer-containing binder copolymer | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-5118750-A | PRESSURE-SENSITIVE ADHESIVE COMPRISING SOLID TACKY MICROSPHERES AND MACROMONOMER-CONTAINING BINDER COPOLYMER | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0454365-A2 | Pressure sensitive adhesive comprising tacky microspheres and macromonomer-containing binder copolymer | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| EP-0419020-A1 | Pressure-sensitive adhesive comprising hollow tacky microspheres and macromonomer-containing binder copolymer | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-03-27 | — | — | EP | disclosed |
| US-4994322-A | Repositionable | MINNESOTA MINING AND MANUFACTURING (US) | 1991-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158375-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | MPO, MUC1, CRYAB | TDP1 2034/4885CHRM1 1844/4885AKR1A1 870/4885 |
| US-11643429-B2 | Compounds and methods for the treatment of ocular disorders | SERPINB1, KLKB1, MPO | TDP1 1989/4885CHRM1 1817/4885AKR1A1 630/4885 |
| US-20230348517-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | SERPINB1, KLKB1, MPO | TDP1 1989/4885CHRM1 1817/4885AKR1A1 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.