SCHEMBL1200223

SCHEMBL1200223

COC(=N)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PNP P00491 4/20 0.71
▸ LMNA P02545 3/20 0.64
▸ SMN1; SMN2 Q16637 2/20 0.64
▸ ADORA1 P30542 2/20 0.64
▸ ALDH1A1 P00352 1/20 0.64
▸ GLA P06280 1/20 0.64
▸ EIF4E P06730 1/20 0.64
▸ CYP3A4 P08684 1/20 0.64
▸ TOP1 P11387 1/20 0.64
▸ TSHR P16473 1/20 0.64
▸ THPO P40225 1/20 0.64
▸ PMP22 Q01453 1/20 0.64
▸ ADORA2A P29274 2/20 0.42
▸ ADORA3 P0DMS8 1/20 0.42
▸ ADORA2B P29275 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12879159 1.00 PNP (0.71) PNPLMNASMN1; SMN2ADORA1ALDH1A1
SCHEMBL12892516 1.00 PNP (0.71) PNPLMNASMN1; SMN2ADORA1ALDH1A1
SCHEMBL10428124 0.88 PNP (0.68) PNPLMNASMN1; SMN2ADORA1ALDH1A1
SCHEMBL12879160 0.85 PNP (0.61) PNPLMNASMN1; SMN2ADORA1ALDH1A1
SCHEMBL12879134 0.85 PNP (0.61) PNPLMNASMN1; SMN2ADORA1ALDH1A1
SCHEMBL13352079 0.85 PNP (0.71) PNPLMNASMN1; SMN2ADORA1ALDH1A1
SCHEMBL27568954 0.85 LMNA (0.71) PNPLMNASMN1; SMN2ADORA1ALDH1A1
SCHEMBL2841654 0.85 LMNA (0.71) PNPLMNASMN1; SMN2ADORA1ALDH1A1
SCHEMBL13320531 0.85 PNP (0.71) PNPLMNASMN1; SMN2ADORA1ALDH1A1
SCHEMBL27568953 0.85 LMNA (0.71) PNPLMNASMN1; SMN2ADORA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118586790-B Scientific and technical element-transformation-structure multidimensional coupling calculation method 南京大学 2024-11-19 — — CN claimed
CN-118675725-A Family member remote accompanying interaction system based on intensive care unit management information 浙江大学医学院附属邵逸夫医院 2024-09-20 — — CN claimed
CN-118586790-A Scientific and technical element-transformation-structure multidimensional coupling calculation method 南京大学 2024-09-03 — — CN claimed
EP-4261831-A1 PREDICTION OF CHEMICAL COMPOUNDS WITH DESIRED PROPERTIES Bayer AG (DE) 2023-10-18 — — EP claimed
CN-116482687-B Amplitude-variable target ISAR imaging translational compensation method based on minimum mean square error 中国科学院空天信息创新研究院 2023-08-15 — — CN claimed
CN-116482687-A Amplitude-variable target ISAR imaging translational compensation method based on minimum mean square error 中国科学院空天信息创新研究院 2023-07-25 — — CN claimed
CN-112492553-B Non-orthogonal access method for MTC user clustering in NB-IoT system 国网江苏省电力工程咨询有限公司 2023-06-27 — — CN claimed
CN-115291546-A Control system of intelligent electric power instrument 帝森克罗德集团有限公司 2022-11-04 — — CN claimed
US-4925930-A ANTICARCINOGENIC AND ANTITUMOR AGENTS NUCLEIC ACID RESEARCH INSTITUTE (US) 1990-05-15 — — US claimed
WO-2025261579-A1 NETWORK NODE, USER EQUIPMENT, AND METHODS PERFORMED THEREIN TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) (SE) 2025-12-26 — — WO disclosed
CN-118586790-B Scientific and technical element-transformation-structure multidimensional coupling calculation method 南京大学 2024-11-19 — — CN disclosed
US-12103216-B2 Fluidic systems, devices and methods for inducing anisotropy in polymeric materials THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2024-10-01 — — US disclosed
CN-118675725-A Family member remote accompanying interaction system based on intensive care unit management information 浙江大学医学院附属邵逸夫医院 2024-09-20 — — CN disclosed
CN-118634747-A Preparation method of self-reporting and self-repairing composite material 重庆大学 2024-09-13 — — CN disclosed
US-20140288295-A1 OLIGOMER CONJUGATES OF HETEROPENTACYCLIC NUCLEOSIDES NEKTAR THERAPEUTICS 2014-09-25 — — US disclosed
US-8778898-B2 Oligomer conjugates of heteropentacyclic nucleosides NEKTAR THERAPEUTICS (US) 2014-07-15 — — US disclosed
US-20130261072-A1 OLIGOMER CONJUGATES OF HETEROPENTACYCLIC NUCLEOSIDES NEKTAR THERAPEUTICS (US) 2013-10-03 — — US disclosed
US-8466276-B2 Oligomer conjugates of heteropentacyclic nucleosides NEKTAR THERAPEUTICS (US) 2013-06-18 — — US disclosed
US-20110039797-A1 Oligomer Conjugates of Heteropentacyclic Nucleosides Nektar Therapetics (US) 2011-02-17 — — US disclosed
US-4925930-A ANTICARCINOGENIC AND ANTITUMOR AGENTS NUCLEIC ACID RESEARCH INSTITUTE (US) 1990-05-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110039797-A1 Oligomer Conjugates of Heteropentacyclic Nucleosides SLC29A2, SLC29A1, GNE PNP 137/4885LMNA 3873/4885SMN1; SMN2 2799/4885
US-20140288295-A1 OLIGOMER CONJUGATES OF HETEROPENTACYCLIC NUCLEOSIDES SLC29A2, SLC29A1, GNE PNP 137/4885LMNA 3873/4885SMN1; SMN2 2799/4885
US-20130261072-A1 OLIGOMER CONJUGATES OF HETEROPENTACYCLIC NUCLEOSIDES GNE, SLC29A2, ABCG2 PNP 152/4885LMNA 3345/4885SMN1; SMN2 2130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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