SCHEMBL1200247

SCHEMBL1200247

c1ccc2c(-c3nc4ccccc4o3)c(-c3nc4ccccc4o3)ccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.54
HPGD P15428 8/20 0.54
HSD17B10 Q99714 8/20 0.54
MAPT P10636 7/20 0.54
NPC1 O15118 5/20 0.54
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
RAB9A P51151 4/20 0.54
TP53 P04637 4/20 0.54
PKM P14618 2/20 0.54
HCRTR1 O43613 1/20 0.54
KDM4E B2RXH2 8/20 0.54
USP2 O75604 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.51
GAA P10253 2/20 0.51
GLA P06280 1/20 0.51
CASP1 P29466 1/20 0.51
CASP7 P55210 1/20 0.51
ESR1 P03372 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20407192 0.84 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10MAPTNPC1
SCHEMBL20405138 0.84 ALDH1A1 (0.49) ALDH1A1HPGDHSD17B10MAPTNPC1
SCHEMBL30682 0.84 ALDH1A1 (0.65) ALDH1A1HPGDHSD17B10MAPTNPC1
SCHEMBL29627559 0.84 ALDH1A1 (0.65) ALDH1A1HPGDHSD17B10MAPTNPC1
SCHEMBL30096340 0.84 ALDH1A1 (0.65) ALDH1A1HPGDHSD17B10MAPTNPC1
SCHEMBL30022809 0.83 ALDH1A1 (0.66) ALDH1A1HPGDHSD17B10MAPTNPC1
SCHEMBL30487873 0.83 KDM4E (0.57) ALDH1A1HPGDHSD17B10MAPTNPC1
SCHEMBL196237 0.83 KDM6B (0.54) ALDH1A1HPGDHSD17B10MAPTNPC1
SCHEMBL15106798 0.83 KDM6B (0.54) ALDH1A1HPGDHSD17B10MAPTNPC1
SCHEMBL987895 0.81 ALDH1A1 (0.68) ALDH1A1HPGDHSD17B10MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1325067-B1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEM CO (US) 2006-09-06 EP claimed
EP-1325067-A1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEMICAL COMPANY (US) 2003-07-09 EP claimed
US-6492032-B1 MIXTURE OF BENZOXAZOLYL STILBENES WITH A BIS(BENZOXAZOLYL)-NAPHTHALENE, BIS(BENZOXAZOLYL)THIOPHENE, A PYRAZOLINE AND/OR A COURMARIN; PHOTOGRAPHIC FILMS EASTMAN CHEMICAL COMPANY 2002-12-10 US claimed
WO-2002031035-A1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEMICAL COMPANY (US) 2002-04-18 WO claimed
US-5817448-A PYRAZOLINE OR BIS/BENZOXAZOLYL/ NAPHTHALENE, THIOPHENE OR STILBENE BASED BRIGHTENER FUJI PHOTO FILM CO., LTD. (JP) 1998-10-06 US claimed
US-5714310-A Photographic support comprising a resin layer containing TiO2 pigments being coated with an alkaline earth metal-containing compound MITSUBISHI PAPER MILLS LIMITED (JP) 1998-02-03 US claimed
EP-0321393-B1 OPTICAL BRIGHTENER DISPERSION CIBA-GEIGY AG (CH) 1993-02-17 EP claimed
EP-0323399-B1 OPTICAL BRIGHTENER DISPERSION CIBA-GEIGY AG (CH) 1993-02-17 EP claimed
US-5173397-A Sharpness of printed images, whiteness, surface properties MITSUBISHI PAPER MILLS LIMITED (JP) 1992-12-22 US claimed
US-5152922-A 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1992-10-06 US claimed
US-5075206-A Fluorescent dye; brightness MITSUBISHI PAPER MILLS LIMITED (JP) 1991-12-24 US claimed
US-5053055-A WHITENER DISPERSION CIBA-GEIGY CORPORATION (US) 1991-10-01 US claimed
US-5051111-A Whitener dispersion CIBA-GEIGY CORPORATION (US) 1991-09-24 US claimed
EP-0252009-B1 1,4-DISTYRYL BENZENE COMPOUNDS AND THEIR MIXTURES WITH OTHER 1,4-DISTYRYL BENZENE COMPOUNDS CIBA-GEIGY AG (CH) 1990-08-01 EP claimed
US-4940469-A Low-foaming composition for finishing synthetic fibres: dye or optical brightener or ultra-violet absorber and alkylene-diamide:ethylene-distearamide CIBA-GEIGY CORPORATION (US) 1990-07-10 US claimed
EP-0328485-A1 Foamless preparation for finishing synthetic fibres CIBA-GEIGY AG (CH) 1989-08-16 EP claimed
EP-0323399-A1 Optical brightener dispersion CIBA-GEIGY AG (CH) 1989-07-05 EP claimed
EP-0321393-A1 Optical brightener dispersion CIBA-GEIGY AG (CH) 1989-06-21 EP claimed
EP-0252009-A1 1,4-Distyryl benzene compounds and their mixtures with other 1,4-distyryl benzene compounds CIBA-GEIGY AG (CH) 1988-01-07 EP claimed
JP-9203984-A None JP disclosed
JP-3091740-A None JP disclosed
JP-9179265-A None JP disclosed
US-11199787-B2 Fluorescent metallic toners and related methods XEROX CORPORATION (US) 2021-12-14 US disclosed
US-11199786-B2 Fluorescent white toners and related methods XEROX CORPORATION (US) 2021-12-14 US disclosed
US-20210294231-A1 FLUORESCENT WHITE TONERS AND RELATED METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2021-09-23 US disclosed
EP-3882702-A1 FLUORESCENT WHITE TONERS AND RELATED METHODS Xerox Corporation (US) 2021-09-22 EP disclosed
EP-2261287-B1 AROMATIC POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN CHEMICALS LTD (JP) 2021-01-27 EP disclosed
EP-2963075-B1 POLYCARBONATE MOLDED ARTICLE TEIJIN LTD (JP) 2018-12-12 EP disclosed
US-9810630-B1 Fluorescent marking gel compositions and methods of use ECOLAB USA INC. (US) 2017-11-07 US disclosed
US-20160075823-A1 POLYCARBONATE MOLDED ARTICLE TEIJIN LIMITED (JP) 2016-03-17 US disclosed
EP-2963075-A1 POLYCARBONATE MOLDED ARTICLE Teijin Limited (JP) 2016-01-06 EP disclosed
US-8697788-B2 Polycarbonate resin composition and molded article thereof TEIJIN CHEMICALS, LTD. (JP) 2014-04-15 US disclosed
US-8415410-B2 Aromatic polycarbonate resin composition and a molded article thereof TEIJIN CHEMICALS, LTD. (JP) 2013-04-09 US disclosed
US-20120095141-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN CHEMICALS, LTD. (JP) 2012-04-19 US disclosed
US-20110028601-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION AND A MOLDED ARTICLE THEREOF TEIJIN CHEMICALS, LTD. (JP) 2011-02-03 US disclosed
EP-2261287-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Teijin Chemicals, Ltd. (JP) 2010-12-15 EP disclosed
US-20100165444-A1 DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2010-07-01 US disclosed
US-7622520-B2 Light reflecting polymeric articles containing benzoxazolyl-napthalene optical brighteners MATTEL, INC (US) 2009-11-24 US disclosed
US-7622520-B2 Light reflecting polymeric articles containing benzoxazolyl-napthalene optical brighteners MATTEL, INC (US) 2009-11-24 US disclosed
US-7615266-B2 Ink jet recording material EIKO EPSON CORPORATION (JP) 2009-11-10 US disclosed
EP-1443080-B1 THERMOPLASTIC RESIN COMPOSITION, MOLDED ARTICLE, AND PROCESS FOR PRODUCING THE SAME TEIJIN CHEMICALS LTD (JP) 2009-07-15 EP disclosed
EP-1557444-B1 AROMATIC POLYCARBONATE RESIN COMPOSITION TEIJIN CHEMICALS LTD (JP) 2009-05-27 EP disclosed
EP-1975692-A1 DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2008-10-01 EP disclosed
EP-1705028-B1 Ink jet recording material SEIKO EPSON CORP (JP) 2008-05-21 EP disclosed
US-20070155888-A1 Aromatic polycarbonate resin composition and process for the production thereof TEIJIN CHEMICALS LTD. (JP) 2007-07-05 US disclosed
US-7189796-B2 With a layered silicate cation-exchanged with an organic cation, a maleic anhydride-styrene copolymer, and a full or partial ester of a fatty acid and polyhydric alcohol; good rigidity and hydrolysis resistance; silicate is highly dispersed TEIJIN CHEMICALS, LTD. (JP) 2007-03-13 US disclosed
US-20060270311-A1 Light reflecting polymeric articles containing benzoxazolyl-napthalene optical brighteners MATTEL, INC 2006-11-30 US disclosed
US-20060270311-A1 Light reflecting polymeric articles containing benzoxazolyl-napthalene optical brighteners MATTEL, INC 2006-11-30 US disclosed
EP-1721923-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION AND PROCESS FOR PRODUCING THE SAME Teijin Chemicals, Ltd. (JP) 2006-11-15 EP disclosed
US-20060216443-A1 Including fumed silica and layer including colloidal silica, and backcoat layer of polyurethane resin SEIKO EPSON CORPORATION 2006-09-28 US disclosed
EP-1705028-A1 Ink jet recording material SEIKO EPSON CORPORATION (JP) 2006-09-27 EP disclosed
US-7108913-B1 Light reflecting polymeric articles containing benzoxazolyl-napthalene optical brighteners MATTEL, INC. (US) 2006-09-19 US disclosed
US-7108913-B1 Light reflecting polymeric articles containing benzoxazolyl-napthalene optical brighteners MATTEL, INC. (US) 2006-09-19 US disclosed
EP-1325067-B1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEM CO (US) 2006-09-06 EP disclosed
EP-1325067-B1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEM CO (US) 2006-09-06 EP disclosed
US-7098263-B2 Thermoplastic resin composition, molded article, and process for producing the same TEIJIN CHEMICALS, LTD. (JP) 2006-08-29 US disclosed
US-20050272903-A1 Aromatic polycarbonate resin composition TEIJIN CHEMICALS LTD. (JP) 2005-12-08 US disclosed
US-20050235429-A1 Method for brightening textile materials BASF AKTIENGESSELLSCHAFT (DE) 2005-10-27 US disclosed
EP-1504149-B1 METHOD FOR BRIGHTENING TEXTILE MATERIALS BASF AG (DE) 2005-08-24 EP disclosed
EP-1557444-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION Teijin Chemicals, Ltd. (JP) 2005-07-27 EP disclosed
EP-1443080-A1 THERMOPLASTIC RESIN COMPOSITION, MOLDED ARTICLE, AND PROCESS FOR PRODUCING THE SAME Teijin Chemicals, Ltd. (JP) 2004-08-04 EP disclosed
US-20040030021-A1 Thermoplastic resin composition, molded article, and process for producing the same TEIJIN CHEMICALS LTD. (JP) 2004-02-12 US disclosed
CN-1469894-A Multi-component optically brightened polyolefin blend �Ϻ���ͨ��ѧ 2004-01-21 CN disclosed
EP-1325067-A1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEMICAL COMPANY (US) 2003-07-09 EP disclosed
EP-1325067-A1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEMICAL COMPANY (US) 2003-07-09 EP disclosed
US-6492032-B1 MIXTURE OF BENZOXAZOLYL STILBENES WITH A BIS(BENZOXAZOLYL)-NAPHTHALENE, BIS(BENZOXAZOLYL)THIOPHENE, A PYRAZOLINE AND/OR A COURMARIN; PHOTOGRAPHIC FILMS EASTMAN CHEMICAL COMPANY 2002-12-10 US disclosed
US-6492032-B1 MIXTURE OF BENZOXAZOLYL STILBENES WITH A BIS(BENZOXAZOLYL)-NAPHTHALENE, BIS(BENZOXAZOLYL)THIOPHENE, A PYRAZOLINE AND/OR A COURMARIN; PHOTOGRAPHIC FILMS EASTMAN CHEMICAL COMPANY 2002-12-10 US disclosed
WO-2002031035-A1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEMICAL COMPANY (US) 2002-04-18 WO disclosed
WO-2002031035-A1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEMICAL COMPANY (US) 2002-04-18 WO disclosed
US-5817448-A PYRAZOLINE OR BIS/BENZOXAZOLYL/ NAPHTHALENE, THIOPHENE OR STILBENE BASED BRIGHTENER FUJI PHOTO FILM CO., LTD. (JP) 1998-10-06 US disclosed
US-5817448-A PYRAZOLINE OR BIS/BENZOXAZOLYL/ NAPHTHALENE, THIOPHENE OR STILBENE BASED BRIGHTENER FUJI PHOTO FILM CO., LTD. (JP) 1998-10-06 US disclosed
US-5714310-A Photographic support comprising a resin layer containing TiO2 pigments being coated with an alkaline earth metal-containing compound MITSUBISHI PAPER MILLS LIMITED (JP) 1998-02-03 US disclosed
JP-H09179265-A SOLUTION HAVING PHOTOGRAPHIC BLEACHING ABILITY AND PROCESSING METHOD FOR SILVER HALIDE PHOTOGRAPHIC SENSITIVE MATERIAL FUJI PHOTO FILM CO LTD 1997-07-11 JP disclosed
US-5547822-A ADDING ALKALINE EARTH COMPOUND TO TITANIUM DIOXIDE, CALCINATION, ACID TREATMENT, SURFACE TREATMENT WITH HYDRATED METAL OXIDE, DRYING, GRINDING, KNEADING PARTICLES WITH THERMOPLASTIC RESIN, AND MELT EXTRUSION MITSUBISHI PAPER MILLS (JP) 1996-08-20 US disclosed
US-5264033-A Sharpness MITSUBISHI PAPER MILLS LTD (JP) 1993-11-23 US disclosed
US-5213888-A Asupport coated with a polyolefin, titanium dioxide and a fluorescent dye MITSUBISHI PAPER MILLS LIMITED (JP) 1993-05-25 US disclosed
EP-0321393-B1 OPTICAL BRIGHTENER DISPERSION CIBA-GEIGY AG (CH) 1993-02-17 EP disclosed
EP-0323399-B1 OPTICAL BRIGHTENER DISPERSION CIBA-GEIGY AG (CH) 1993-02-17 EP disclosed
US-5173397-A Sharpness of printed images, whiteness, surface properties MITSUBISHI PAPER MILLS LIMITED (JP) 1992-12-22 US disclosed
US-5152922-A 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
US-5106989-A Discoloration inhibition MITSUBISHI PAPER MILLS LIMITED (JP) 1992-04-21 US disclosed
US-5075206-A Fluorescent dye; brightness MITSUBISHI PAPER MILLS LIMITED (JP) 1991-12-24 US disclosed
US-5053055-A WHITENER DISPERSION CIBA-GEIGY CORPORATION (US) 1991-10-01 US disclosed
US-5051111-A Whitener dispersion CIBA-GEIGY CORPORATION (US) 1991-09-24 US disclosed
JP-H0391740-A PHOTOGRAPHIC BASE MITSUBISHI PAPER MILLS LTD 1991-04-17 JP disclosed
EP-0252009-B1 1,4-DISTYRYL BENZENE COMPOUNDS AND THEIR MIXTURES WITH OTHER 1,4-DISTYRYL BENZENE COMPOUNDS CIBA-GEIGY AG (CH) 1990-08-01 EP disclosed
US-4940469-A Low-foaming composition for finishing synthetic fibres: dye or optical brightener or ultra-violet absorber and alkylene-diamide:ethylene-distearamide CIBA-GEIGY CORPORATION (US) 1990-07-10 US disclosed
EP-0323399-A1 Optical brightener dispersion CIBA-GEIGY AG (CH) 1989-07-05 EP disclosed
EP-0321393-A1 Optical brightener dispersion CIBA-GEIGY AG (CH) 1989-06-21 EP disclosed
EP-0246551-A3 BIS-BENZOXAZOLYLNAPHTHALENES CONTAINING SULFONATE OR SULFONAMIDE GROUPS, PROCESS FOR THEIR PREPARATION, AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-10 EP disclosed
US-4791205-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1988-12-13 US disclosed
US-4791205-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1988-12-13 US disclosed
EP-0252009-A1 1,4-Distyryl benzene compounds and their mixtures with other 1,4-distyryl benzene compounds CIBA-GEIGY AG (CH) 1988-01-07 EP disclosed
EP-0246551-A2 Bis-benzoxazolylnaphthalenes containing sulfonate or sulfonamide groups, process for their preparation, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-11-25 EP disclosed
EP-0044996-B1 MIXTURES OF OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1984-06-06 EP disclosed
US-4447350-A Mixtures of optical brighteners and their use HOECHST AKTIENGESELLSCHAFT (DE) 1984-05-08 US disclosed
EP-0044996-A1 Mixtures of optical brighteners HOECHST AKTIENGESELLSCHAFT (DE) 1982-02-03 EP disclosed
US-4058408-A Bis-benzoxazolyl-naphthalenes as optical brighteners CIBA-GEIGY CORPORATION (US) 1977-11-15 US disclosed
US-3993659-A Bis-benzoxazolyl-naphthalenes as optical brighteners CIBA-GEIGY CORPORATION (US) 1976-11-23 US disclosed
US-3993659-A Bis-benzoxazolyl-naphthalenes as optical brighteners CIBA-GEIGY CORPORATION (US) 1976-11-23 US disclosed