Bromomethane

Bromomethane

SCHEMBL120034

CBr.O=C(OCC(=CO)c1ccccc1)C(O)(c1cccc(F)c1)c1cccc(F)c1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 2/20 0.39
CHRM2 P08172 4/20 0.37
CHRM3 P20309 4/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
CHRM1 P11229 3/20 0.37
POLB P06746 2/20 0.37
CHRM4 P08173 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
MAPT P10636 2/20 0.36
ALDH1A1 P00352 2/20 0.36
KCNK3 O14649 1/20 0.34
HPGD P15428 2/20 0.34
GPR52 Q9Y2T5 1/20 0.34
LMNA P02545 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3911903 0.96 KCNN4 (0.41) KCNN4CHRM2CHRM3MEN1KMT2A
Bromomethane SCHEMBL7081897 0.91 CHRM2 (0.36) CHRM2CHRM3MEN1KMT2ACHRM1
Bromomethane SCHEMBL14142455 0.89 LMNA (0.42) CHRM3MEN1KMT2APOLBSMN1; SMN2
Bromomethane SCHEMBL118164 0.87 CHRM2 (0.39) KCNN4CHRM2CHRM3MEN1KMT2A
SCHEMBL7081056 0.87 MEN1 (0.36) KCNN4CHRM2CHRM3MEN1KMT2A
Bromomethane SCHEMBL7087263 0.86 SCN5A (0.37) CHRM2CHRM3MEN1KMT2ACHRM1
Bromomethane SCHEMBL119398 0.86 KCNN4 (0.38) KCNN4CHRM2CHRM3MEN1KMT2A
SCHEMBL14142417 0.85 LMNA (0.45) CHRM3MEN1KMT2ASMN1; SMN2MAPT
Bromomethane SCHEMBL7086475 0.84 PPARG (0.34) CHRM2CHRM3MEN1KMT2ACHRM1
Bromomethane SCHEMBL7085461 0.84 NPC1 (0.39) CHRM2CHRM3MEN1KMT2ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3508239-B1 ADAPTER, INHALANT APPARATUS AND ATOMIZER BOEHRINGER INGELHEIM INT (DE) 2020-12-23 EP disclosed
EP-2614848-B1 Inhaler and capsule for an inhaler BOEHRINGER INGELHEIM INT (DE) 2020-07-01 EP disclosed
EP-2026761-B1 INHALANT PROPELLANT-FREE AEROSOL FORMULATION BOEHRINGER INGELHEIM INT (DE) 2020-04-15 EP disclosed
EP-2066380-B1 INHALER BOEHRINGER INGELHEIM INT (DE) 2019-10-09 EP disclosed
EP-2004262-B1 CONTAINER FOR INHALER, AND MULTIDOSE INHALER BOEHRINGER INGELHEIM INT (DE) 2019-08-14 EP disclosed
EP-3508239-A1 ADAPTER, INHALANT APPARATUS AND ATOMIZER Boehringer Ingelheim International GmbH (DE) 2019-07-10 EP disclosed
EP-3189869-B1 POWDER INHALER BOEHRINGER INGELHEIM INT (DE) 2019-07-03 EP disclosed
EP-2173421-B1 INHALATOR BOEHRINGER INGELHEIM INT (DE) 2019-04-10 EP disclosed
EP-2004260-B1 MEDICAMENT LOADER AND MULTI-DOSE POWDER INHALER BOEHRINGER INGELHEIM INT (DE) 2019-03-20 EP disclosed
EP-2007456-B1 MOUTHPIECE FOR AN INHALER BOEHRINGER INGELHEIM PHARMA (DE) 2018-10-17 EP disclosed
WO-2006037736-A1 NOVEL POWDER INHALATION PREPARATIONS BASED ON MODIFIED LACTOSE BLENDS THAT ARE USED AS ADJUVANTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-04-13 WO disclosed
WO-2006037738-A1 MODIFYING SURFACES OF LACTOSE SERVING AS AN AUXILIARY AGENT TO BE USED FOR POWDER INHALANTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-04-13 WO disclosed
EP-1634041-A1 MEASURING DEVICE FOR NON-DESTRUCTIVELY DETERMINING THE NET WEIGHT IN TABLETS Boehringer Ingelheim International GmbH (DE) 2006-03-15 EP disclosed
WO-2005111005-A1 NOVEL ENANTIOMERICALLY PURE BETA-AGONISTS, METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF A DRUG BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-24 WO disclosed
WO-2005102349-A1 PHARMACEUTICAL COMBINATIONS CONTAINING BENZOXAZINE FOR TREATING RESPIRATORY DISEASES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-03 WO disclosed
WO-2005097126-A1 COMPOUNDS FOR TREATING PROLIFERATIVE PROCESSES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-10-20 WO disclosed
WO-2004106870-A1 MEASURING DEVICE FOR NONDESTRUCTIVELY DETERMINING THE WEIGHT-IN QUANTITY IN CAPSULES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-12-09 WO disclosed
EP-1484586-A1 Measuring device for non-destructively determining the net weight in tablets BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2004-12-08 EP disclosed
EP-1328524-A2 NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS Boehringer Ingelheim Pharma GmbH & Co.KG (DE) 2003-07-23 EP disclosed
WO-2002032898-A2 NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-04-25 WO disclosed