Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.53 |
| ▸ | CACNB1 | Q02641 | 5/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12019733 | 0.94 | CACNA2D1 (0.48) | CACNA2D1CACNA1BCACNB1CACNA1CL3MBTL1 | |
| SCHEMBL12818114 | 0.88 | TSHR (0.48) | CACNA2D1CACNA1BCACNB1CACNA1CL3MBTL1 | |
| SCHEMBL5268108 | 0.88 | L3MBTL1 (0.61) | CACNA2D1CACNA1BCACNB1CACNA1CL3MBTL1 | |
| SCHEMBL12003631 | 0.87 | CACNA1B (0.53) | CACNA2D1CACNA1BCACNB1CACNA1CL3MBTL1 | |
| SCHEMBL12003808 | 0.87 | CACNA2D1 (0.53) | CACNA2D1CACNA1BCACNB1CACNA1CL3MBTL1 | |
| SCHEMBL12304095 | 0.86 | KMT2A (0.48) | CACNA2D1CACNA1BCACNB1CACNA1CL3MBTL1 | |
| SCHEMBL14817943 | 0.80 | MEN1 (0.52) | L3MBTL1TSHRPOLBHPGDPKM | |
| SCHEMBL12003810 | 0.80 | L3MBTL1 (0.55) | CACNA2D1CACNA1BCACNB1CACNA1CL3MBTL1 | |
| SCHEMBL12243883 | 0.77 | TSHR (0.55) | L3MBTL1TSHRPOLBALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL6164887 | 0.75 | L3MBTL1 (0.56) | CACNA2D1CACNA1BCACNB1CACNA1CL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629149-B2 | Oxopiperazine derivatives for the treatment of pain and epilepsy | ZALICUS PHARMACEUTICALS LTD. (CA) | 2014-01-14 | — | — | US | claimed |
| US-20120220605-A1 | OXOPIPERAZINE DERIVATIVES FOR THE TREATMENT OF PAIN AND EPILEPSY | ZALICUS PHARMACEUTICALS LTD. (CA) | 2012-08-30 | — | — | US | claimed |
| US-8629149-B2 | Oxopiperazine derivatives for the treatment of pain and epilepsy | ZALICUS PHARMACEUTICALS LTD. (CA) | 2014-01-14 | — | — | US | disclosed |
| US-20120220605-A1 | OXOPIPERAZINE DERIVATIVES FOR THE TREATMENT OF PAIN AND EPILEPSY | ZALICUS PHARMACEUTICALS LTD. (CA) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220605-A1 | OXOPIPERAZINE DERIVATIVES FOR THE TREATMENT OF PAIN AND EPILEPSY | CACNA1H, CACNG7, CACNA1I | CACNA2D1 34/4885CACNA1B 5/4885CACNB1 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.