Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 3/20 | 0.44 |
| ▸ | BRAF | P15056 | 3/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12004567 | 0.96 | ESR1 (0.57) | ESR1ESR2MAOBGAAMEN1 | |
| SCHEMBL12004978 | 0.93 | MAOB (0.55) | ESR1ESR2MAOBGAAMEN1 | |
| SCHEMBL12005115 | 0.90 | MAOB (0.46) | ESR1ESR2MAOBGAAMEN1 | |
| SCHEMBL12004654 | 0.90 | MAOB (0.55) | ESR1ESR2MAOBMEN1KMT2A | |
| SCHEMBL12004569 | 0.87 | ESR1 (0.68) | ESR1ESR2MEN1LMNAHPGD | |
| SCHEMBL12005784 | 0.87 | ESR1 (0.68) | ESR1ESR2MEN1LMNAHPGD | |
| SCHEMBL12004221 | 0.86 | FYN (0.48) | ESR1ESR2MAOBGAAMEN1 | |
| SCHEMBL12004206 | 0.85 | ESR1 (0.61) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL13609946 | 0.85 | MAOB (0.60) | ESR1ESR2MAOBMEN1HPGD | |
| SCHEMBL12005164 | 0.82 | ESR1 (0.70) | ESR1ESR2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816135-B2 | Trisphenol compound | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | NCOR1, NCOR2, NCOA1 | ESR1 40/4885ESR2 18/4885MAOB 3970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.