⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28038330 | 0.97 | LMNA (0.47) | — | |
| Water SCHEMBL28001085 | 0.97 | — | — | |
| Methane SCHEMBL27983532 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL9459532 | 0.97 | — | — | |
| Ethane SCHEMBL668882 | 0.95 | LMNA (0.38) | — | |
| SCHEMBL28288434 | 0.89 | ABCC4 (0.34) | — | |
| SCHEMBL3090511 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL9459862 | 0.82 | LMNA (0.46) | — | |
| SCHEMBL27455689 | 0.82 | LMNA (0.52) | — | |
| SCHEMBL4528856 | 0.80 | TSHR (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3641826-B1 | METHODS OF PRODUCING DRUG-CARRYING POLYMER SCAFFOLDS AND PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2023-12-06 | — | — | EP | claimed |
| CN-104334596-A | Polymer and nanogel materials and methods of making and using the same | JOHNSON & JOHNSON VISION CARE | 2015-02-04 | — | — | CN | claimed |
| CN-102171589-A | Ionic silicone hydrogels having improved hydrolytic stability | JOHNSON & JOHNSON VISION CARE | 2011-08-31 | — | — | CN | claimed |
| CN-1133688-C | Optical disk waste recovery composition and application thereof | 财团法人工业技术研究院 | 2004-01-07 | — | — | CN | claimed |
| CN-1312312-A | Optical disk waste recovery composition and application thereof | INST OF IND TECHN (CN) | 2001-09-12 | — | — | CN | claimed |
| CN-1064366-C | Preparation of 3-amino -1 -hydroxypropane -1, 1 -diphosphonic acid | DONG KOOK PHARM CO LTD (KR) | 2001-04-11 | — | — | CN | claimed |
| CN-1175582-A | Preparation of 3-amino -1 -hydroxypropane -1, 1 -diphosphonic acid | DONG KOOK PHARM CO LTD (KR) | 1998-03-11 | — | — | CN | claimed |
| CN-111819168-A | Compound, curing agent composition, resin composition, coating composition, and resin cured product | 旭化成株式会社 | 2020-10-23 | — | — | CN | disclosed |
| US-20180162859-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | ATXCO, INC. | 2018-06-14 | — | — | US | disclosed |
| CN-108025574-A | Thermal recording medium | 三光株式会社 | 2018-05-11 | — | — | CN | disclosed |
| US-9926318-B2 | Tetracyclic autotaxin inhibitors | PHARMAKEA, INC. (US) | 2018-03-27 | — | — | US | disclosed |
| EP-2267062-B1 | SUPRAMOLECULAR POLYMERS CONTAINING QUADRUPLE HYDROGEN BONDING UNITS IN THE POLYMER BACKBONE | SUPRAPOLIX BV (NL) | 2017-10-25 | — | — | EP | disclosed |
| CN-107250220-A | Silicone particles, the manufacture method of Silicone particles, sealant for liquid crystal dripping process and liquid crystal display cells | 积水化学工业株式会社 | 2017-10-13 | — | — | CN | disclosed |
| CN-1163145-A | Inhibiting agent for vascular formation | SENJI SEIYAKU K K (JP) | 1997-10-29 | — | — | CN | disclosed |
| EP-0769955-A1 | NON-ANTIGENIC AMINE DERIVED POLYMERS AND POLYMER CONJUGATES | ENZON, INC. (US) | 1997-05-02 | — | — | EP | disclosed |
| EP-0752991-A1 | INDENO[1,2-e]PYRAZINE-4-ONES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-01-15 | — | — | EP | disclosed |
| WO-1996000080-A1 | NON-ANTIGENIC AMINE DERIVED POLYMERS AND POLYMER CONJUGATES | ENZON, INC. (US) | 1996-01-04 | — | — | WO | disclosed |
| WO-1995026349-A1 | INDENO[1,2-e]PYRAZINE-4-ONES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1995-10-05 | — | — | WO | disclosed |
| EP-0263481-A2 | Process for the preparation of isocyanates | BAYER AG (DE) | 1988-04-13 | — | — | EP | disclosed |
| US-3985711-A | Dicarboxylic compounds having 2,4-quinazolinedione rings and polyester resins derived therefrom | INSTITUT FRANCAIS DU PETROLE, DES CARBURANTS ET LUBRIFIANTS ET ENTREPRISE DE RECHERCHES ET D'ACTIVITIES PETROLIERES ELF (FR) | 1976-10-12 | — | — | US | disclosed |