Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1150112 | 0.98 | CYP3A4 (0.51) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL3781027 | 0.97 | CYP3A4 (0.50) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| Water SCHEMBL27627263 | 0.97 | CYP3A4 (0.50) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL27082392 | 0.90 | CYP3A4 (0.49) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL3974699 | 0.88 | CYP3A4 (0.42) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL28790902 | 0.88 | CYP3A4 (0.53) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL9731952 | 0.82 | CYP3A4 (0.47) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL5164929 | 0.82 | CYP3A4 (0.50) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL9235986 | 0.81 | ALDH1A1 (0.40) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL9497372 | 0.80 | CYP3A4 (0.59) | CYP3A4L3MBTL1TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536103-B2 | Liquid extreme pressure additive | THE LUBRIZOL CORPORATION | 2013-09-17 | — | — | US | disclosed |
| US-20110028363-A1 | Liquid Extreme Pressure Additive | THE LUBRIZOL CORPORATION | 2011-02-03 | — | — | US | disclosed |
| EP-2250242-A2 | LIQUID EXTREME PRESSURE ADDITIVE | The Lubrizol Corporation (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009111235-A2 | LIQUID EXTREME PRESSURE ADDITIVE | THE LUBRIZOL CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |
| EP-0359522-B1 | OIL-SOLUBLE PHOSPHORUS ANTIWEAR ADDITIVES FOR LUBRICANTS | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0359522-A1 | Oil-soluble phosphorus antiwear additives for lubricants | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1990-03-21 | — | — | EP | disclosed |
| US-4857214-A | Oil-soluble phosphorus antiwear additives for lubricants | Ethylk Petroleum Additives, Inc. (US) | 1989-08-15 | — | — | US | disclosed |