Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12017337 | 1.00 | HPGD (0.46) | HPGDHTTLMNATSHRPAX8 | |
| SCHEMBL1845703 | 0.81 | MAPT (0.40) | HPGDHTTLMNAKDM4EALDH1A1 | |
| SCHEMBL1845704 | 0.81 | MAPT (0.40) | HPGDHTTLMNAKDM4EALDH1A1 | |
| SCHEMBL28911367 | 0.67 | PARP1 (0.49) | LMNATSHRPAX8KDM4EALDH1A1 | |
| SCHEMBL279422 | 0.66 | — | — | |
| SCHEMBL24956336 | 0.66 | HPGD (0.67) | HPGDHTTKMT2AMEN1MAPT | |
| SCHEMBL27977195 | 0.66 | GAA (0.40) | LMNATSHRPAX8KDM4EALDH1A1 | |
| SCHEMBL1844496 | 0.66 | LMNA (0.38) | LMNATSHRPAX8KDM4EALDH1A1 | |
| SCHEMBL1844495 | 0.66 | LMNA (0.38) | LMNATSHRPAX8KDM4EALDH1A1 | |
| SCHEMBL1844474 | 0.64 | LMNA (0.40) | HPGDLMNATSHRPAX8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102149703-B | Anti-cancer drugs and uses relating thereto for metastatic malignant melanoma and other cancers | LAILA NUTRACEUTICALS | 2014-09-10 | — | — | CN | claimed |
| US-8258119-B2 | Anti-cancer drugs and uses relating thereto for metastatic malignant melanoma and other cancers | Kasina Laila Innova Pharmaceuticals (IN) | 2012-09-04 | — | — | US | claimed |
| CN-102149703-A | Anti-cancer drugs and uses relating thereto for metastatic malignant melanoma and other cancers | LAILA NUTRACEUTICALS | 2011-08-10 | — | — | CN | claimed |
| CN-102149703-B | Anti-cancer drugs and uses relating thereto for metastatic malignant melanoma and other cancers | LAILA NUTRACEUTICALS | 2014-09-10 | — | — | CN | disclosed |
| CN-102149703-A | Anti-cancer drugs and uses relating thereto for metastatic malignant melanoma and other cancers | LAILA NUTRACEUTICALS | 2011-08-10 | — | — | CN | disclosed |