Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 4/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | NPY4R | P50391 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14078001 | 0.90 | MEN1 (0.56) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL12673518 | 0.88 | MEN1 (0.59) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL14078000 | 0.88 | MEN1 (0.54) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL10098708 | 0.88 | MEN1 (0.54) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL27105521 | 0.87 | FPR2 (0.55) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL12017845 | 0.87 | MEN1 (0.53) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL17663659 | 0.86 | MEN1 (0.60) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL29593395 | 0.85 | MEN1 (0.61) | MEN1KMT2ABLMUSP2POLB | |
| Rhodamine B SCHEMBL10000882 | 0.85 | MEN1 (0.61) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL3903552 | 0.85 | MEN1 (0.61) | MEN1KMT2ABLMUSP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744236-B2 | Photolabile compounds | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-08-29 | — | — | US | disclosed |
| US-20150032045-A1 | PHOTOLABILE COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-01-29 | — | — | US | disclosed |
| US-20150032045-A1 | PHOTOLABILE COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-01-29 | — | — | US | disclosed |
| US-20120220922-A1 | PHOTOLABILE COMPOUNDS | UNIVERSIDAD DE BUENOS AIRES (AR) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150032045-A1 | PHOTOLABILE COMPOUNDS | VIP, EPCAM, L1CAM | MEN1 834/4885KMT2A 1348/4885BLM 2821/4885 |
| US-20120220922-A1 | PHOTOLABILE COMPOUNDS | VIP, EPCAM, L1CAM | MEN1 834/4885KMT2A 1348/4885BLM 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.