SCHEMBL12019595

SCHEMBL12019595

C/C(C=O)=C\C(C)Cc1ccc2c(c1)OCC2

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.48
CHRM1 P11229 1/20 0.48
CHRNB2 P17787 1/20 0.48
CHRM3 P20309 1/20 0.48
CHRNA4 P43681 1/20 0.48
NPSR1 Q6W5P4 1/20 0.40
ACACB O00763 2/20 0.39
MMP1 P03956 1/20 0.39
TAAR1 Q96RJ0 2/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
OGA O60502 2/20 0.35
ERN1 O75460 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2168564 0.81 NPSR1 (0.61) NPSR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL2168560 0.81 NPSR1 (0.61) NPSR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL11477974 0.76 CHRM2 (0.50) CHRM2CHRM1CHRNB2CHRM3CHRNA4
SCHEMBL14185999 0.75 TAAR1 (0.61) CHRM2CHRM1CHRNB2CHRM3CHRNA4
SCHEMBL2562965 0.75 TAAR1 (0.61) CHRM2CHRM1CHRNB2CHRM3CHRNA4
SCHEMBL14314404 0.73 ACACB (0.46) CHRM2CHRM1CHRNB2CHRM3CHRNA4
SCHEMBL29833531 0.72 CHRM2 (0.58) CHRM2CHRM1CHRNB2CHRM3CHRNA4
SCHEMBL5035088 0.72 CHRM2 (0.58) CHRM2CHRM1CHRNB2CHRM3CHRNA4
SCHEMBL27197708 0.72 TAAR1 (0.61) CHRM2CHRM1CHRNB2CHRM3CHRNA4
SCHEMBL19891712 0.70 CHRM2 (0.45) CHRM2CHRM1CHRNB2CHRM3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1970368-B1 METHOD FOR PRODUCING OLEFIN COMPOUND SUMITOMO CHEMICAL CO (JP) 2012-08-29 EP disclosed