SCHEMBL14314404

SCHEMBL14314404

CC(C=O)Cc1ccc2c(c1)CCO2

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACACB O00763 2/20 0.46
RAB9A P51151 2/20 0.45
NPC1 O15118 1/20 0.45
POLB P06746 1/20 0.45
CYP2D6 P10635 1/20 0.45
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
KCNH2 Q12809 1/20 0.42
CHRM2 P08172 1/20 0.42
CHRM1 P11229 1/20 0.42
CHRNB2 P17787 1/20 0.42
CHRM3 P20309 1/20 0.42
CHRNA4 P43681 1/20 0.42
ERN1 O75460 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
DYRK1A Q13627 1/20 0.40
DYRK2 Q92630 1/20 0.40
DYRK1B Q9Y463 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5018746 0.83 ACACB (0.48) ACACBRAB9ANPC1POLBCYP2D6
SCHEMBL29804006 0.80 TAAR1 (0.59) ACACBRAB9ANPC1POLBCYP2D6
SCHEMBL14072835 0.80 ACACB (0.49) ACACBRAB9ANPC1POLBCYP2D6
SCHEMBL2561330 0.80 TAAR1 (0.59) ACACBRAB9ANPC1POLBCYP2D6
SCHEMBL10368509 0.80 CYP2D6 (0.41) ACACBRAB9ANPC1POLBCYP2D6
SCHEMBL24443666 0.79 CYP2D6 (0.47) ACACBRAB9ANPC1POLBCYP2D6
SCHEMBL13003656 0.79 CYP2D6 (0.47) ACACBRAB9ANPC1POLBCYP2D6
SCHEMBL851164 0.78 RAB9A (0.48) RAB9ANPC1POLBKCNH2CHRM2
SCHEMBL31338945 0.78 RAB9A (0.48) RAB9ANPC1POLBKCNH2CHRM2
SCHEMBL21893190 0.78 TAAR1 (0.45) ACACBRAB9ANPC1POLBCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2119714-B1 METHOD OF RETAINING THE QUALITY OF 2-METHYL-3-(3,4-METHYLENEDIOXYPHENYL)PROPANAL AND PROCESS FOR PRODUCING THE SAME UBE INDUSTRIES (JP) 2012-12-19 EP disclosed