⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658713 | 0.74 | — | — | |
| Furan-2(5H)-One SCHEMBL25302 | 0.71 | — | — | |
| SCHEMBL4520159 | 0.71 | — | — | |
| SCHEMBL7485477 | 0.71 | PKM (0.48) | — | |
| SCHEMBL9051083 | 0.70 | CA1 (0.46) | — | |
| SCHEMBL8121232 | 0.70 | — | — | |
| SCHEMBL2634409 | 0.70 | — | — | |
| Furan-2(5H)-One SCHEMBL31686414 | 0.69 | — | — | |
| Furan-2(5H)-One SCHEMBL28520105 | 0.69 | — | — | |
| SCHEMBL31511764 | 0.67 | CA1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203770-B1 | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating hyperplasia and other diseases | UPJOHN CO (US) | 2005-03-09 | — | — | EP | claimed |
| EP-0668860-B1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | UPJOHN CO (US) | 2002-09-11 | — | — | EP | claimed |
| EP-0252476-B1 | Trans-6-[2-(N-heteroaryl-3,5-disubstituted) pyrazol-4-yl)-ethyl]- or ethenyl] tetrahydro-4-hydroxypyran-2-one-derivatives a process for their preparation and the use thereof | WARNER LAMBERT CO (US) | 1994-02-02 | — | — | EP | claimed |
| EP-0211416-B1 | NOVEL HMG-COA REDUCTASE INHIBITORS | MERCK & CO. INC. (US) | 1991-10-16 | — | — | EP | claimed |
| EP-0061800-B1 | ANTI SRS-A CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | FISONS plc (GB) | 1985-08-28 | — | — | EP | claimed |
| CN-121574135-A | Method for synthesizing 7-oxa-2-azabicyclo [3.3.1] non-3-alkene-1-alcohol by rare earth catalysis | 北京化工大学 | 2026-02-27 | — | — | CN | disclosed |
| EP-3661601-A1 | METHODS FOR INCREASING FERTILITY | Newsouth Innovations Pty Limited (AU) | 2020-06-10 | — | — | EP | disclosed |
| EP-3558312-A1 | METHODS FOR ENHANCING VASCULAR DENSITY | Newsouth Innovations Pty Limited (AU) | 2019-10-30 | — | — | EP | disclosed |
| WO-2019023748-A1 | METHODS FOR INCREASING FERTILITY | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2019-02-07 | — | — | WO | disclosed |
| WO-2018112541-A1 | METHODS FOR ENHANCING VASCULAR DENSITY | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2018-06-28 | — | — | WO | disclosed |
| US-20170153180-A1 | COMPOSITIONS, METHODS AND DEVICES THEREOF FOR FLUORESCENT ANALYSIS OF GUNSHOT RESIDUE | DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) | 2017-06-01 | — | — | US | disclosed |
| EP-3068364-A1 | SENESCENCE AND SENESCENCE ASSOCIATED SECRETORY PHENOTYPE | NewSouth Innovations Pty Limited (AU) | 2016-09-21 | — | — | EP | disclosed |
| WO-2003070719-A1 | BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2003-08-28 | — | — | WO | disclosed |
| WO-2002058694-A9 | METHOD OF TREATING HEMATOLOGIC TUMORS AND CANCERS USING BETA LAPACHONE | DANA FARBER CANCER INST INC (US) | 2003-04-17 | — | — | WO | disclosed |
| US-20030036515-A1 | Method of treating hematologic tumors and cancers | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2003-02-20 | — | — | US | disclosed |
| US-20020169135-A1 | Method of treating hematologic tumors and cancers | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2002-11-14 | — | — | US | disclosed |
| WO-2002058694-A2 | METHOD OF TREATING HEMATOLOGIC TUMORS AND CANCERS USING BETA LAPACHONE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
| EP-0054316-A1 | Lacton compounds, process for their preparation and their use as flavouring or aromatising ingredients | FIRMENICH SA (CH) | 1982-06-23 | — | — | EP | disclosed |
| US-4277608-A | Method of preparing 4a-arylhexahydro-1H-2-pyrindines and 4a-aryloctahydroisoquinolines | ELI LILLY AND COMPANY (US) | 1981-07-07 | — | — | US | disclosed |
| US-4236009-A | Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |