Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 19/20 | 0.55 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.46 |
| ▸ | GNA15 | P30679 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021215 | 0.90 | FFAR1 (0.53) | FFAR1ANO1GNA15AKR1B1FFAR4 | |
| SCHEMBL12021118 | 0.88 | FFAR1 (0.64) | FFAR1 | |
| SCHEMBL17386331 | 0.82 | MAOB (0.54) | FFAR1 | |
| SCHEMBL17386334 | 0.82 | MAOB (0.54) | FFAR1 | |
| SCHEMBL14980205 | 0.80 | FFAR1 (0.63) | FFAR1 | |
| SCHEMBL14273217 | 0.80 | FFAR1 (0.63) | FFAR1 | |
| SCHEMBL12021109 | 0.79 | FFAR1 (0.62) | FFAR1 | |
| SCHEMBL12348753 | 0.78 | FFAR1 (0.61) | FFAR1 | |
| SCHEMBL17429707 | 0.78 | MAPT (0.42) | FFAR1 | |
| SCHEMBL5944103 | 0.76 | FFAR1 (0.64) | FFAR1ANO1AKR1B1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893582-B1 | Compounds, their pharmaceutical compositions and their use in treating metabolic disorders | AMGEN INC (US) | 2011-12-14 | — | — | EP | disclosed |