Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995131 | 0.92 | USP2 (0.52) | USP2SMN1; SMN2ESR2NR1H2KDM4E | |
| SCHEMBL20765932 | 0.92 | USP2 (0.47) | USP2SMN1; SMN2ESR2NR1H2KDM4E | |
| SCHEMBL14800964 | 0.92 | USP2 (0.52) | USP2SMN1; SMN2ESR2NR1H2KDM4E | |
| Hydrochloric Acid SCHEMBL26689433 | 0.90 | USP2 (0.50) | USP2SMN1; SMN2ESR2NR1H2KDM4E | |
| Tetrahydrofuran SCHEMBL29063445 | 0.88 | USP2 (0.57) | USP2SMN1; SMN2ESR2NR1H2KDM4E | |
| SCHEMBL31080015 | 0.87 | USP2 (0.50) | USP2SMN1; SMN2ESR2NR1H2KDM4E | |
| SCHEMBL27006656 | 0.85 | USP2 (0.46) | USP2SMN1; SMN2ESR2NR1H2KDM4E | |
| SCHEMBL29938153 | 0.85 | USP2 (0.39) | USP2SMN1; SMN2ESR2NR1H2KDM4E | |
| SCHEMBL2292608 | 0.84 | USP2 (0.52) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL123032 | 0.84 | ESR2 (0.54) | USP2SMN1; SMN2ESR2NR1H2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3953 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707770-A | Method for synthesizing 3-amino azetidine-1-tert-butyl formate | 大连双硼医药化工有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119431325-A | 3- (1H-pyrazol-1-yl) azetidine compound and synthetic method thereof | 诚达药业股份有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-118619919-A | Preparation method of 1- (azetidine-3-yl) -4, 4-difluoropiperidine hydrochloride | 宁波职业技术学院 | 2024-09-10 | — | — | CN | claimed |
| CN-118530153-A | Preparation method of 1-Boc-3-azetidinone | 上海津力药业股份有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-117003681-A | Inhibitor intermediate and synthesis method thereof | 苏州汉德创宏生化科技有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116693437-A | Synthesis method of N-Boc-3-azetidineacetic acid | 安徽大学 | 2023-09-05 | — | — | CN | claimed |
| CN-116082359-A | Method for preparing 9-carbonyl-5-oxo-2, 8-aza [3.5] nonane-2-carboxylic acid tert-butyl ester | 南通药明康德医药科技有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-110577515-B | Synthesis method of 4- (azetidin-3-yl) -1-methylpiperazine-2-one dihydrochloride | 南通大学 | 2022-05-17 | — | — | CN | claimed |
| CN-114085176-A | Synthesis method of 5-Boc-5-azaspiro [2.3] hexane-1-carboxylic acid | 吉尔生化（上海）有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-112920205-A | Preparation of azetidine isobenzofuran compound by continuous reaction | 浙江瑞博制药有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-110683978-A | Preparation method of 3-nitrile methylene azetidine-1-tert-butyl carbonate | 西安医学院 | 2020-01-14 | — | — | CN | claimed |
| CN-110577515-A | Synthesis method of 4- (azetidin-3-yl) -1-methylpiperazine-2-one dihydrochloride | 南通大学 | 2019-12-17 | — | — | CN | claimed |
| EP-2683723-B1 | SPIROCYCLIC ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC (US) | 2016-05-25 | — | — | EP | claimed |
| CN-105017268-A | 2-tertbutyloxycarbonyl-7-carbonyl-5-O-2-azaspiro(3.4)octane synthesis method | WUXI APPTEC CO LTD | 2015-11-04 | — | — | CN | claimed |
| EP-2683723-A1 | SPIROCYCLIC ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2014-01-15 | — | — | EP | claimed |
| US-8466115-B2 | Spirocyclic isoxazoline derivatives as antiparasitic agents | ZOETIS LLC (US) | 2013-06-18 | — | — | US | claimed |
| WO-2012120399-A1 | SPIROCYCLIC ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | PFIZER INC. (US) | 2012-09-13 | — | — | WO | claimed |
| US-20120232026-A1 | SPIROCYCLIC ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | PFIZER INC. (US) | 2012-09-13 | — | — | US | claimed |
| US-20260146037-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | SHANGHAI YIDIAN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2026-05-28 | — | — | US | disclosed |
| WO-2002012187-A1 | NOVEL PHENYLHETEROAZETIDINES, USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2002-02-14 | — | — | WO | disclosed |