Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL28603193 | 0.98 | ESR2 (0.52) | ESR2NR1H2ADORA1USP2SMN1; SMN2 | |
| Acetonitrile SCHEMBL29109665 | 0.92 | NR1H2 (0.50) | ESR2NR1H2ADORA1USP2SMN1; SMN2 | |
| SCHEMBL13160 | 0.89 | ESR2 (0.48) | ESR2NR1H2ADORA1USP2SMN1; SMN2 | |
| SCHEMBL27669441 | 0.89 | USP2 (0.56) | ESR2NR1H2ADORA1USP2SMN1; SMN2 | |
| SCHEMBL14800964 | 0.89 | USP2 (0.52) | ESR2NR1H2ADORA1USP2SMN1; SMN2 | |
| SCHEMBL31028 | 0.89 | USP2 (0.56) | ESR2NR1H2ADORA1USP2SMN1; SMN2 | |
| SCHEMBL1336913 | 0.88 | HPGD (0.49) | ESR2NR1H2ADORA1USP2SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27841683 | 0.87 | USP2 (0.55) | ESR2NR1H2ADORA1USP2SMN1; SMN2 | |
| SCHEMBL30707004 | 0.86 | HPGD (0.51) | ESR2NR1H2ADORA1USP2SMN1; SMN2 | |
| Ethylene SCHEMBL3832936 | 0.85 | USP2 (0.53) | ESR2NR1H2ADORA1USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3346 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777136-B | 1, 3-Disubstituted tetrahydropyrrole derivative and preparation method and application thereof | 沈阳药科大学 | 2025-04-29 | — | — | CN | claimed |
| CN-119753050-A | Preparation method of 3-ketotetrahydrofuran | 中国科学院青岛生物能源与过程研究所 | 2025-04-04 | — | — | CN | claimed |
| CN-119614650-A | R-aminotransferase and application thereof in asymmetric synthesis of chiral N-heterocyclic amine compound | 沈阳药科大学 | 2025-03-14 | — | — | CN | claimed |
| CN-119592535-A | Omega-aminotransferase ancestral enzyme mutant for efficiently catalyzing and synthesizing (R) -chiral amine compound and application thereof | 浙江科技大学 | 2025-03-11 | — | — | CN | claimed |
| CN-119574680-A | Mass spectrum detection method for N-heterocyclic ketone and/or N-heterocyclic chiral amino compound and application thereof | 北京衍微科技有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119023611-A | Real-time monitoring method for ketone-amine conversion reaction process and application thereof | 北京衍微科技有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-116103257-B | Reductive amination enzyme mutant and application thereof in synthesis of alkylated pyrrolidine chiral amine | 中国科学院天津工业生物技术研究所 | 2024-10-29 | — | — | CN | claimed |
| CN-118755684-A | Catalytic enzyme for producing chiral aromatic amine, N-heterocyclic amine and derivatives thereof with high optical purity, and preparation method and application thereof | 杭州微远生物科技有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-115974746-B | Synthesis method of tosufloxacin tosylate intermediate | 天地恒一制药股份有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-114277008-B | (R) -selective transaminase and application thereof | 弈柯莱生物科技(集团)股份有限公司 | 2024-09-24 | — | — | CN | claimed |
| EP-1987152-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CHIRAL AMINES | LONZA AG (CH) | 2010-05-26 | — | — | EP | claimed |
| US-20090246837-A1 | Process for The Preparation of Optically Active Chiral Amines | LONZA AG (CH) | 2009-10-01 | — | — | US | claimed |
| CN-101384723-A | Process for the preparation of optically active chiral amines | LONZA AG (CH) | 2009-03-11 | — | — | CN | claimed |
| EP-1987152-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CHIRAL AMINES | Lonza AG (CH) | 2008-11-05 | — | — | EP | claimed |
| EP-1897956-A1 | Process for preparation of optically active amines by optical resolution of racemic amines employing a bacterial omega-transaminase | Lonza AG (CH) | 2008-03-12 | — | — | EP | claimed |
| WO-2007093372-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CHIRAL AMINES | LONZA AG (CH) | 2007-08-23 | — | — | WO | claimed |
| EP-1818411-A1 | Process for the preparation of optically active chiral amines | Lonza AG (CH) | 2007-08-15 | — | — | EP | claimed |
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-01 | — | — | US | claimed |
| US-20050288316-A1 | Beta-carbolines as growth hormone secretagogue receptor (GHSR) antagonists | BIOVITRUM AB (SE) | 2005-12-29 | — | — | US | claimed |
| WO-2005048916-A2 | TETRAHYDROSPIRO-BETA-CARBOLINE-1,3 '-PYRROLIDINE DERIVATIVES AND THEIR USE IN GHSR-RELATED DISORDERS | BIOVITRUM AB (SE) | 2005-06-02 | — | — | WO | claimed |