SCHEMBL12031847

SCHEMBL12031847

COc1ccc(C2(c3ccc(OC(=O)Oc4ccc(C(C)(C)c5ccc(OC(C)=O)cc5)cc4)cc3)CC(C)CC(C)(C)C2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
KMT2A Q03164 2/20 0.37
HPGD P15428 2/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP2C9 P11712 1/20 0.37
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.33
CNR2 P34972 1/20 0.33
GAA P10253 1/20 0.32
CHRNA1 P02708 1/20 0.32
CHRNG P07510 1/20 0.32
CHRNB1 P11230 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15705247 1.00 ESR1 (0.46) ESR1ESR2KMT2AHPGDMAPT
SCHEMBL12021605 1.00 ESR1 (0.46) ESR1ESR2KMT2AHPGDMAPT
SCHEMBL15705246 1.00 ESR1 (0.46) ESR1ESR2KMT2AHPGDMAPT
SCHEMBL14064751 0.90 ESR1 (0.49) ESR1ESR2KMT2AHPGDMAPT
SCHEMBL12021689 0.90 ESR1 (0.56) ESR1ESR2KMT2AHPGDMAPT
SCHEMBL22651381 0.90 ESR1 (0.56) ESR1ESR2KMT2AHPGDMAPT
SCHEMBL17447226 0.88 GAA (0.43) ESR1ESR2KMT2AHPGDMAPT
SCHEMBL12590930 0.88 ESR1 (0.51) ESR1ESR2KMT2AHPGDMAPT
SCHEMBL16158987 0.88 ESR1 (0.46) ESR1ESR2KMT2AHPGDMAPT
SCHEMBL12590933 0.87 ESR1 (0.50) ESR1ESR2KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9665020-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-05-30 US disclosed
US-20150277249-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-10-01 US disclosed
US-8840986-B2 Laminate coated with radiation-hardenable printing ink or printing lacquer and moulded piece BAYER MATERIALSCIENCE AG (DE) 2014-09-23 US disclosed
US-8722289-B2 Electrophotographic photoreceptor and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-05-13 US disclosed
US-8580878-B2 Radiation-curable printing ink or printing varnish MARABU GMBH & CO. KG (DE) 2013-11-12 US disclosed
US-20110311271-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2011-12-22 US disclosed
US-20110118377-A1 RADIATION-CURABLE PRINTING INK OR PRINTING VARNISH MARABU GMBH & CO. KG (DE) 2011-05-19 US disclosed
US-20110117350-A1 LAMINATE COATED WITH RADIATION-HARDENABLE PRINTING INK OR PRINTING LACQUER AND MOULDED PIECE BAYER MATERIALSCIENCE AG 2011-05-19 US disclosed
US-7462681-B1 Polycyanurate compositions THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-12-09 US disclosed
US-7262489-B2 Three-dimensionally formed circuit sheet, component and method for manufacturing the same POLYMATECH CO., LTD. (JP) 2007-08-28 US disclosed