Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MDH1 | P40925 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15705247 | 0.88 | ESR1 (0.46) | GAALMNAESR1ESR2TSHR | |
| SCHEMBL12021605 | 0.88 | ESR1 (0.46) | GAALMNAESR1ESR2TSHR | |
| SCHEMBL12031847 | 0.88 | ESR1 (0.46) | GAALMNAESR1ESR2TSHR | |
| SCHEMBL15705246 | 0.88 | ESR1 (0.46) | GAALMNAESR1ESR2TSHR | |
| SCHEMBL22651381 | 0.85 | ESR1 (0.56) | GAALMNAESR1ESR2TSHR | |
| SCHEMBL12021689 | 0.85 | ESR1 (0.56) | GAALMNAESR1ESR2TSHR | |
| SCHEMBL13373969 | 0.82 | GAA (0.48) | GAALMNATDP1KMT2AMAPT | |
| SCHEMBL19766172 | 0.81 | ESR1 (0.61) | GAALMNAESR1ESR2KMT2A | |
| SCHEMBL14106818 | 0.79 | ESR1 (0.46) | GAAESR1ESR2TSHRKMT2A | |
| SCHEMBL14064751 | 0.79 | ESR1 (0.49) | GAALMNAESR1ESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160018746-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMATION DEVICE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-01-21 | — | — | US | disclosed |