SCHEMBL12040652

SCHEMBL12040652

CCC(C)(C)Oc1ccc(C(C)(C)c2ccc(OC(=O)C(C)(C)CC)c(C)c2)cc1C

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
VDR P11473 7/20 0.42
HDAC6 Q9UBN7 6/20 0.36
HDAC3 O15379 5/20 0.36
AR P10275 4/20 0.35
FBP1 P09467 1/20 0.35
ESR1 P03372 1/20 0.35
HDAC1 Q13547 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14679466 0.92 CYP2C19 (0.39) VDRHDAC6HDAC3ARFBP1
SCHEMBL17087217 0.91 VDR (0.40) VDRHDAC6HDAC3ARFBP1
SCHEMBL10291402 0.90 VDR (0.42) VDRHDAC6HDAC3ARFBP1
SCHEMBL12907945 0.90 VDR (0.42) VDRHDAC6HDAC3ARFBP1
SCHEMBL14701777 0.88 VDR (0.41) VDRHDAC6HDAC3ARFBP1
SCHEMBL15381906 0.86 VDR (0.44) VDRHDAC6HDAC3ARESR1
SCHEMBL13179880 0.86 VDR (0.33) VDRHDAC6
SCHEMBL13758548 0.83 VDR (0.41) VDRHDAC6HDAC3ARFBP1
SCHEMBL13951768 0.82 BCHE (0.32) VDRESR1MEN1ALDH1A1KMT2A
SCHEMBL13988702 0.81 VDR (0.40) VDRHDAC6HDAC3ARFBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11287756-B2 Positive charging electrophotographic photoreceptor, electrophotographic cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-29 US disclosed
US-20170336724-A1 PHTHALOCYANINE CRYSTAL, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE-FORMING DEVICE USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2017-11-23 US disclosed
US-20170285498-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-10-05 US disclosed
EP-2698671-B1 CHARGE-TRANSPORTING SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY CARTRIDGE, AND IMAGING DEVICE MITSUBISHI CHEM CORP (JP) 2016-04-27 EP disclosed
US-8846282-B2 Phthalocyanine crystal, and electrophotographic photoreceptor, electrophotographic photoreceptor cartridge and image-forming device using the same MITSUBISHI CHEMICAL CORPORATION (JP) 2014-09-30 US disclosed
EP-2698671-A1 CHARGE-TRANSPORTING SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY CARTRIDGE, AND IMAGING DEVICE Mitsubishi Chemical Corporation (JP) 2014-02-19 EP disclosed
US-8369755-B2 Developing device and image forming apparatus using the developing device RICOH COMPANY, LTD. (JP) 2013-02-05 US disclosed
US-8288066-B2 Electroconductive support with a photosensitive layer of an arylamine-based compound; high sensitivity, chargeability, residual potential, light resistance MITSUBISHI CHEMICAL CORPORATION (JP) 2012-10-16 US disclosed
US-20120257907-A1 PHTHALOCYANINE CRYSTAL, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE-FORMING DEVICE USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-10-11 US disclosed
US-20110299888-A1 IMAGE FORMING APPARATUS KYOCERA MITA CORPORATION (JP) 2011-12-08 US disclosed
US-7888455-B2 Polycarbonate copolymer, method for producing the same, molded body, optical material, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2011-02-15 US disclosed
US-20080193867-A1 Electrophotographic Photoreceptor and Image-Forming Apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2008-08-14 US disclosed